7151-19-1 Usage
Description
1H-Pyrrole-2-carboxamide,N,1-dimethyl-(9CI), also known as N,1-dimethylpyrrole-2-carboxamide, is a chemical compound with the molecular formula C7H10N2O. It belongs to the class of organic compounds known as pyrrole-2-carboxamides and is a derivative of pyrrole, a heterocyclic aromatic organic compound. 1H-Pyrrole-2-carboxamide,N,1-dimethyl-(9CI) is used in various fields, including pharmaceuticals and agrochemicals. Due to its potential health hazards, it is important to handle this compound with care and proper management.
Uses
Used in Pharmaceutical Industry:
1H-Pyrrole-2-carboxamide,N,1-dimethyl-(9CI) is used as a pharmaceutical intermediate for the synthesis of various drugs and drug candidates. Its unique chemical structure and properties make it a valuable component in the development of new therapeutic agents.
Used in Agrochemical Industry:
1H-Pyrrole-2-carboxamide,N,1-dimethyl-(9CI) is used as an agrochemical intermediate for the synthesis of various pesticides and crop protection agents. Its chemical properties contribute to the development of effective and targeted agrochemicals to protect crops from pests and diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 7151-19-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,1,5 and 1 respectively; the second part has 2 digits, 1 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 7151-19:
(6*7)+(5*1)+(4*5)+(3*1)+(2*1)+(1*9)=81
81 % 10 = 1
So 7151-19-1 is a valid CAS Registry Number.
InChI:InChI=1/C7H10N2O/c1-8-7(10)6-4-3-5-9(6)2/h3-5H,1-2H3,(H,8,10)
7151-19-1Relevant articles and documents
Rhodium-catalyzed oxidative cycloaddition of benzamides and alkynes via C-H/N-H activation
Hyster, Todd K.,Rovis, Tomislav
supporting information; experimental part, p. 10565 - 10569 (2010/09/17)
The oxidative cycloaddition of benzamides and alkynes has been developed. The reaction utilizes Rh(III) catalysts in the presence of Cu(II) oxidants, and is proposed to proceed by N-H metalation of the amide followed by ortho C-H activation. The resultant rhodacycle undergoes alkyne insertion to form isoquinolones in good yield. The reaction is tolerant of extensive substitution on the amide, alkyne, and arene, including halides, silyl ethers, and unprotected aldehydes as substituents. Unsymmetrical alkynes proceed with excellent regioselectivity, and heteroaryl carboxamides are tolerated leading to intriguing scaffolds for medicinal chemistry. A series of competition experiments shed further light on the mechanism of the transformation and reasons for selectivity.
