71559-14-3

Basic information

• Product Name: Ethanone, 2-azido-1-(4-bromophenyl)-
• Synonyms: Ethanone,2-azido-1-(4-bromophenyl);2-azido-4'-bromoacetophenone;2-azido-1-(4'-bromophenyl)ethanone;2-azido-1-(4-bromophenyl)ethan-1-one
• CAS NO: 71559-14-3
• Molecular Formula: C8H6BrN3O
• Molecular Weight: 240.059
• Mol File: 71559-14-3.mol
• Article Data: 46

Chemical Properties

• CAS DataBase Reference: Ethanone, 2-azido-1-(4-bromophenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 2-azido-1-(4-bromophenyl)-(71559-14-3)
• EPA Substance Registry System: Ethanone, 2-azido-1-(4-bromophenyl)-(71559-14-3)

Safety Data

• Hazardous Substances Data: 71559-14-3(Hazardous Substances Data)

Upstream product

• 99-73-0 para-bromophenacyl bromide 
• 876-27-7 4-chlorophenyl acetate 
• 98545-70-1 2-azido-1-(4-bromophenyl)ethan-1-ol 
• 4209-02-3 1-(4-bromophenyl)-2-chloroethan-1-one 
• 2039-82-9 1-bromo-4-ethenyl-benzene 
• 117465-34-6 2-bromo-1-(4-bromophenyl)ethanol 
• 99-90-1 para-bromoacetophenone 
• 98475-05-9 α-tosyloxy-4-bromoacetophenone 

Downstream Products

• 23071-76-3 1-(4-Dimethylaminophenylimino-)-2-keto-2-(4-bromphenyl-)-propionitril 
• 55327-32-7 2-(4-bromo-phenyl)-oxazole-4-carbaldehyde 
• 586-76-5 4-Bromobenzoic acid 
• 1210046-23-3 1-(4-bromophenyl)-2-(4-phenyl-1H-1,2,3-triazole-1-yl)-1-ethanone 
• 1400866-58-1 1-(4-bromophenyl)-2-[(4-(1-hydroxyethyl)-1H-1,2,3-triazole-1-yl)]-1-ethanone 
• 931966-96-0 C₉H₆BrNOS 
• 1620058-94-7 ethyl 3-azido-4-(4-bromophenyl)-2-hydroxy-2-methyl-4-oxobutanoate 
• 55368-57-5 4-bromo-N-[2-(4-bromophenyl)-2-oxoethyl]benzamide 
• 99-90-1 para-bromoacetophenone 
• 1122-91-4 4-bromo-benzaldehyde 

Relevant articles and documents

Indole-linked 1,2,3-triazole derivatives efficiently modulate COX-2 protein and PGE2 levels in human THP-1 monocytes by suppressing AGE-ROS-NF-kβ nexus

Aims: AGEs augment inflammatory responses by activating inflammatory cascade in monocytes, and hence lead to vascular dysfunction. The current study aims to study a plausible role and mechanism of a new library of indole-tethered 1,2,3-triazoles 2-13 in A

New 2,9-disubstituted-1,10-phenanthroline derivatives with anticancer activity by selective targeting of telomeric G-quadruplex DNA

Fifteen new 1,10-phenanthrolines disubstituted at positions 2 and 9 via amide bonds with different heterocycles have been designed and synthesized as G-quadruplex DNA stabilizers. Ten compounds were evaluated for the in vitro anticancer activity against 60 human tumor cell lines panel, four of them showing a very good inhibitory activity on several cell lines. To assess the ability of the most active compounds to interact with G-quadruplex DNA (G4-DNA), circular dichroism experiments were performed. The potency of the compounds to stabilize the G4-DNA has been shown from the thermal denaturation experiments. The mechanism of compounds binding to DNA and to G4-DNA was theoretically investigated by molecular docking studies. The experimental results demonstrated excellent capacity of the two compounds bearing two pyridin-3-yl residues (methylated and non-methylated) to act as selective G-quadruplex binders with promising anticancer activity.

Carbon isotope labeling of carbamates by late-stage [11C], [13C] and [14C]carbon dioxide incorporation

A general procedure for the late-stage [11C], [13C] and [14C]carbon isotope labeling of cyclic carbamates is reported. This protocol allows the incorporation of carbon dioxide, the primary source of carbon-14 and carbon-11 radioisotopes, in a direct, cost-effective and sustainable manner. A disconnection/reconnection strategy, involving ring opening/isotopic closure, was also implemented.