71718-88-2

Basic information

• Product Name: N-BENZYL-N-(3-PYRIDYLMETHYLENE)AMINE
• Synonyms: (E)-1-phenyl-N-(pyridin-3-ylmethylene)methanamine;N-BENZYL-N-(3-PYRIDYLMETHYLENE)AMINE;1-Phenyl-N-(pyridin-3-ylmethylene)methanamine
• CAS NO: 71718-88-2
• Molecular Formula: C₁₃H₁₂N₂
• Molecular Weight: 196.2478
• Mol File: 71718-88-2.mol
• Article Data: 21

Chemical Properties

• Boiling Point: 333.8 °C at 760 mmHg
• Flash Point: 155.6 °C
• Appearance: /
• Density: 1.01 g/cm³
• Vapor Pressure: 0.000259mmHg at 25°C
• Refractive Index: 1.567
• Storage Temp.: 2-8°C
• CAS DataBase Reference: N-BENZYL-N-(3-PYRIDYLMETHYLENE)AMINE(CAS DataBase Reference)
• NIST Chemistry Reference: N-BENZYL-N-(3-PYRIDYLMETHYLENE)AMINE(71718-88-2)
• EPA Substance Registry System: N-BENZYL-N-(3-PYRIDYLMETHYLENE)AMINE(71718-88-2)

Safety Data

• Hazardous Substances Data: 71718-88-2(Hazardous Substances Data)

Usage

General Description

N-BENZYL-N-(3-PYRIDYLMETHYLENE)AMINE is a chemical compound with the formula C16H16N2. It is a benzyl-derivative of the amine compound with a pyridylmethylene group. N-BENZYL-N-(3-PYRIDYLMETHYLENE)AMINE is often used as a reagent in organic synthesis and chemical research, particularly in the development of pharmaceuticals and agrochemicals. It is also used as a ligand in coordination chemistry and as a building block for the creation of complex organic molecules. N-BENZYL-N-(3-PYRIDYLMETHYLENE)AMINE is considered to be a potentially hazardous and harmful substance, and proper safety measures should be taken when handling and using it in a laboratory setting.

InChI:InChI=1/C13H12N2/c1-2-5-12(6-3-1)9-15-11-13-7-4-8-14-10-13/h1-8,10-11H,9H2

Upstream product

• 500-22-1 3-pyridinecarboxaldehyde 
• 100-46-9 benzylamine 
• 622-79-7 benzyl azide 
• 100-47-0 benzonitrile 
• 3099-31-8 nicotinyl chloride 
• 100-55-0 3-hydroxymethylpyridin 

Downstream Products

• 141120-48-1 (2S)-N-benzyl-2,3-dihydro-2-(3-pyridyl)-4-pyridone 
• 183016-48-0 diethyl (benzylamino)(pyridin-3-yl)methylphosphonate 
• 181178-60-9 (benzylamino-pyridin-3-yl-methyl)-phosphonic acid diphenyl ester 
• 63361-56-8 1-phenyl-N-(pyridin-3-ylmethyl)methanamine 
• 271583-67-6 2-(benzylamino)-2-(pyridin-3-yl)acetonitrile 
• 42977-21-9 1,2-bis(3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluorodecyl)disulfide 
• 494-52-0 Anabasine 
• 141120-60-7 (2S)-N-benzyl-2-(3-pyridyl)-4-piperidinone 
• 40179-50-8 (2S)-N-4'-nitrobenzoyl-2-(3-pyridyl)-4-piperidine 
• 31944-77-1 (2S)-N-benzyl-2-(3-pyridyl)-piperidine 

Relevant articles and documents

Efficient Co-Catalyzed Double Hydroboration of Nitriles: Application to One-Pot Conversion of Nitriles to Aldimines

The commercially available and bench-stable Co(acac)2/dpephos system is employed as a precatalyst for selective and efficient room temperature hydroboration of organic nitriles with HBPin to produce a series of N,N-diborylamines [RN(BPin)2], which react in situ with aldehydes to give aldimines. Formation of aldimines from N,N-diborylamines does not require a dehydrating agent, is applicable to a wide range of N,N-diborylamine and aldehyde substrates and is highly chemoselective, being unaffected by various common functional groups, such as alkenes, alkynes, secondary amines, ketones, esters, amides, carboxylic acids, pyridines, nitriles, and nitro compounds. The overall transformation represents a synthetically valuable approach to aldimines from nitriles and can be performed in a sequential one-pot manner, tolerating ester, lactone, carboxamide and unactivated alkene functionalities.

Selective aerobic oxidation of halides and amines with an inorganic-ligand supported zinc catalyst

A practical, efficient and environmentally benign catalytic protocol for the oxidative cross-coupling reaction of halides with amines, oxidative self-coupling of amines and oxidation of halides was developed with inorganic-ligand supported ZnPOM (NH4)4[ZnMo6O18(OH)6] using molecular oxygen. This method mainly utilizes an inorganic polymolybdate ligand to support the Zn2+ ion, avoiding the use of complicated organic ligands.

Mechanochemical lignin-mediated strecker reaction

A mechanochemical Strecker reaction involving a wide range of aldehydes (aromatic, heteroaromatic and aliphatic), amines, and KCN afforded a library of α-aminonitriles upon mechanical activation. This multicomponent process was efficiently activated by li