7182-29-8

Basic information

• Product Name: 5-Benzofuranol, 2-phenyl-
• CAS NO: 7182-29-8
• Molecular Formula: C14H10O2
• Molecular Weight: 210.232
• Mol File: 7182-29-8.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 5-Benzofuranol, 2-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Benzofuranol, 2-phenyl-(7182-29-8)
• EPA Substance Registry System: 5-Benzofuranol, 2-phenyl-(7182-29-8)

Safety Data

• Hazardous Substances Data: 7182-29-8(Hazardous Substances Data)

Upstream product

• 37167-62-7 bromo-phenyl-acetic acid methyl ester 
• 672-13-9 2-hydroxy-5-methoxybenzaldehyde 
• 23030-43-5 2,5-dihydroxy-1-iodobenzene 
• 536-74-3 phenylacetylene 
• 4316-37-4 1,1,-diethoxy-1-phenylethane 
• 106-51-4 p-benzoquinone 
• 98-86-2 acetophenone 
• 13196-10-6 benzofuran-5-ol 
• 108-90-7 chlorobenzene 
• 120552-88-7 4-hydroxy-4-(phenylethynyl)cyclohexa-2,5-dien-1-one 
• 7196-01-2 4-(1-phenylvinyl)morpholine 
• 7182-32-3 2-phenyl-5-methoxybenzo[b]furan 
• 94-02-0 ethyl 3-oxo-3-phenylpropionate 
• 4610-75-7 5-hydroxyl‐2‐phenylbenzofuran-3-carboxylate ethyl ester 

Downstream Products

• 1072895-42-1 5-(2-methylbut-3-yn-2-yloxy)-2-phenylbenzofuran 
• 7182-32-3 2-phenyl-5-methoxybenzo[b]furan 
• 19312-07-3 2.5-dihydroxy-bibenzyl 
• 1448962-63-7 4-([1,4'-bipiperidin]-1'-ylmethyl)-2-phenylbenzofuran-5-yl trifluoromethanesulfonate 
• 1580443-51-1 C₂₈H₃₄N₂O₄ 
• 1580443-53-3 N-(20-amino-3,6,9,12,15,18-hexaoxaicosyl)-1′-((5-hydroxy-2-phenylbenzofuran-4-yl)methyl)-(1,4′-bipiperidine)-4-carboxamide 
• 1580443-52-2 N-(20-azido-3,6,9,12,15,18-hexaoxaicosyl)-1'-((5-hydroxy-2-phenylbenzofuran-4-yl)methyl)(1,4'-bipiperidine)-4-carboxamide 
• 1448962-45-5 4-((1,4'-bipiperidin)-1'-ylmethyl)-2-phenylbenzofuran-5-ol 

Relevant articles and documents

Synthesis and biological evaluation of 2-arylbenzofuran derivatives as potential anti-Alzheimer’s disease agents

Alzheimer's disease (AD) is a type of progressive dementia caused by degeneration of the nervous system. A single target drug usually does not work well. Therefore, multi-target drugs are designed and developed so that one drug can specifically bind to mu

Synthesis of Benzofurans from Ketones and 1,4-Benzoquinones

Benzofuran derivatives can be synthesized through the sequential Michael addition and cyclization of 1,3-dicarbonyl compounds with 1,4-benzoquinones. However, ketones are rarely used in this reaction because of their low nucleophilicities. In this study, this problem was solved by utilizing triethyl orthoformate, which enabled the formation of a vinyl ethyl ether as an additive. As a result, the nucleophilicity of ketones increased. Many important 5-hydroxybenzofuran derivatives, which were not readily available by synthesis in the past, were also prepared via these newly established reactions. (Figure presented.) .

A direct approach to 5-hydroxybenzofurans via a platinum-catalyzed domino rearrangement/5-endo-dig cyclization reaction of quinols

(Chemical Equation Presented) A highly efficient and atom-economical construction of 2-substituted 5-hydroxybenzofurans was accomplished by employing a platinum-catalyzed domino dienone-phenol rearrangement/5-endo-dig cyclization reaction of quinols beari