718632-80-5Relevant articles and documents
Homopolymeric pyrrolidine-amide oligonucleotide mimics: Fmoc-synthesis and DNA/RNA binding properties
Tan, T. H. Samuel,Worthington, Roberta J.,Pritchard, Robin G.,Morral, Jordi,Micklefield, Jason
, p. 239 - 248 (2008/03/14)
By chemically modifying or replacing the backbone of oligonucleotides it is possible to modulate the DNA and RNA recognition properties and fine-tune the physiochemical properties of oligomers. This is important because it challenges our understanding of