71980-88-6 Usage
Description
5-Bromo-2-(2-hydroxyethylaminoacetylamino)-2'-fluorobenzophenone is a complex organic compound that serves as an intermediate in the synthesis of pharmaceuticals. It is characterized by the presence of a bromo and fluoro substituent on the benzophenone core, along with an ethylaminoacetylamino and hydroxyethylamino group, which contribute to its unique chemical properties and potential applications.
Uses
Used in Pharmaceutical Industry:
5-Bromo-2-(2-hydroxyethylaminoacetylamino)-2'-fluorobenzophenone is used as an intermediate in the synthesis of Haloxazolam (H104000), a sleep-inducing agent. It is structurally related to other sedative-hypnotic drugs such as Oxazolam and Cloxazolam (C587475). 5-Bromo-2-(2-hydroxyethylaminoacetylamino)-2'-fluorobenzophenone plays a crucial role in the development of medications aimed at treating sleep disorders and promoting relaxation.
As a sedative, hypnotic, and controlled substance (depressant), 5-Bromo-2-(2-hydroxyethylaminoacetylamino)-2'-fluorobenzophenone contributes to the formulation of medications that help alleviate anxiety and induce sleep, providing relief for individuals suffering from insomnia and other sleep-related issues. Its role in the synthesis of Haloxazolam highlights its importance in the pharmaceutical industry for creating effective treatments for sleep and anxiety disorders.
Check Digit Verification of cas no
The CAS Registry Mumber 71980-88-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,1,9,8 and 0 respectively; the second part has 2 digits, 8 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 71980-88:
(7*7)+(6*1)+(5*9)+(4*8)+(3*0)+(2*8)+(1*8)=156
156 % 10 = 6
So 71980-88-6 is a valid CAS Registry Number.
71980-88-6Relevant articles and documents
Electroanalysis of 10-bromo-11b-(2-fluorophenyl-one)-2,3,7,1b-tetrahydrooxazolo [3,2][1,4]-benzodiazepin-6-(5H) (Haloxazolam)
Volke,Oelschlager
, p. 824 - 828 (2007/10/02)
Sulfuric acid (2.7 m) with 10% (vol.) ethylene glycol dimethylether provides sufficient stability of the electroactive form of haloxalozam (1) and may be used as a supporting electrolyte for its DCP or DPP determination in pharmaceutical preparations. The polarographic behaviour of 1 was investigated: the polarographic curves are markedly influenced by the hydrolysis of the original inactive form 1 to the iminium species A and further to the substituted benzophenone B in which both heterocyclic rings have been opened. The mechanism and the kinetics of these hydrolytic reactions have been studied and an interpretation has been suggested. The recommended determination is based on the 2-electron reduction of A. The lower sensitivity limit is 2.5·10-5 mol·l-1 in the DC mode and 2.5·10-6 mol·l-1 in DPP. In the analysis of single tablets the relative standard deviation S(rel) is 1.8 for 5 mg and 3.8 for 10 mg tablets (both DCP). Therefore, this polarographic method is suitable for the content uniformity test.
