72053-00-0 Usage
Description
1-(4-bromophenyl)-2-(pyridin-2-yl)ethanone is a chemical compound characterized by its molecular formula C13H10BrNO. It is a yellow solid that serves as a vital intermediate in the synthesis of pharmaceuticals and other organic compounds. 1-(4-bromophenyl)-2-(pyridin-2-yl)ethanone is widely utilized in organic chemistry research and is also employed in the production of various drugs and agrochemicals. Due to its potential hazards, it is essential to handle this chemical with care and adhere to proper safety protocols.
Uses
Used in Pharmaceutical Synthesis:
1-(4-bromophenyl)-2-(pyridin-2-yl)ethanone is used as an intermediate in the pharmaceutical industry for the synthesis of various drugs. Its unique chemical structure allows it to be a key component in the development of new medications, contributing to the advancement of healthcare.
Used in Agrochemical Production:
In the agrochemical industry, 1-(4-bromophenyl)-2-(pyridin-2-yl)ethanone is used as a starting material for the production of different agrochemicals. Its role in this sector is crucial for the development of effective products that protect crops and enhance agricultural productivity.
Used in Organic Chemistry Research:
1-(4-bromophenyl)-2-(pyridin-2-yl)ethanone is also an important compound in the field of organic chemistry research. It is employed in various experimental setups to study its properties, reactivity, and potential applications in the synthesis of novel organic compounds. This research contributes to the broader understanding of chemical reactions and the development of new synthetic methods.
Check Digit Verification of cas no
The CAS Registry Mumber 72053-00-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,2,0,5 and 3 respectively; the second part has 2 digits, 0 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 72053-00:
(7*7)+(6*2)+(5*0)+(4*5)+(3*3)+(2*0)+(1*0)=90
90 % 10 = 0
So 72053-00-0 is a valid CAS Registry Number.
72053-00-0Relevant articles and documents
Synthesis of functionalised 4H-quinolizin-4-ones via tandem Horner-Wadsworth-Emmons olefination/cyclisation
Muir, Calum W.,Kennedy, Alan R.,Redmond, Joanna M.,Watson, Allan J. B.
supporting information, p. 3337 - 3340 (2013/06/05)
4H-Quinolizin-4-ones are a unique class of heterocycle with valuable physicochemical properties and which are emerging as key pharmacophores for a range of biological targets. A tandem Horner-Wadsworth-Emmons olefination/cyclisation method has been developed to allow facile access to substituted 4H-quinolizin-4-ones encoded with a range of functional groups.
Substituent and temperature controlled tautomerism of 2-phenacyl-pyridine: The hydrogen bond as a configurational lock of (Z)-2-(2-hydroxy-2-phenylvinyl)pyridine
Kolehmainen, Erkki,Osmiaowski, Borys,Nissinen, Maija,Kauppinen, Reijo,Gawinecki, Ryszard
, p. 2185 - 2191 (2007/10/03)
2-Phenacylpyridines substituted in the benzene ring are in equilibrium with (Z)-2-(2-hydroxy-2-phenylvinyl)pyridines when dissolved in chloroform. The substituent affects significantly the tautomeric equilibrium [the amount of the enolimine form stabilized by the intramolecular hydrogen bond is 1 and 92% for R = p-N(CH2)4 and p-NO2, respectively]. The negative logarithm of the tautomeric equilibrium constant, KT, is linearly dependent on the Hammett σ substituent constants. The dependence of KT vs. temperature is exponential in character: the more electron-withdrawing is the substituent, the more distinct is the influence of temperature. Unexpectedly, the tautomer present in the crystalline state is not the same for all compounds studied (it is the ketimine one for those carrying strong electron-donor groups). Among the different ab initio methods used to calculate the enthalpy of the proton transfer in chloroform solution, MP2/6-31G** gives the best results.
