7214-52-0

Basic information

• Product Name: CIS-3,5-DIMETHYLCYCLOHEXANONE
• Synonyms: CIS-3,5-DIMETHYLCYCLOHEXANONE;Cyclohexanone, 3,5-dimethyl-, (3R,5S)-rel-
• CAS NO: 7214-52-0
• Molecular Formula: C₈H₁₄O
• Molecular Weight: 126.2
• Mol File: 7214-52-0.mol
• Article Data: 22

Chemical Properties

• Appearance: /
• CAS DataBase Reference: CIS-3,5-DIMETHYLCYCLOHEXANONE(CAS DataBase Reference)
• NIST Chemistry Reference: CIS-3,5-DIMETHYLCYCLOHEXANONE(7214-52-0)
• EPA Substance Registry System: CIS-3,5-DIMETHYLCYCLOHEXANONE(7214-52-0)

Safety Data

• Hazardous Substances Data: 7214-52-0(Hazardous Substances Data)

Usage

Uses

This compound is useful in biological studies in the bioprospecting of bioactive metabolites from from Monochaetia karstenii.

Upstream product

• 18951-83-2 (-)-trans-(2R)-bromo-(5R)-methylcyclohexanone 
• 78-59-1 3,5,5-Trimethylcyclohex-2-en-1-one 
• 1123-09-7 3,5-dimethyl-2-cyclohexen-1-one 
• 767-13-5 3,5-dimethylcyclohexanol 
• 108-68-9 3,5-Dimethylphenol 
• 2320-30-1 3,5-dimethylcyclohexanone 
• 64-17-5 ethanol 
• 5441-52-1 3,5-dimethylcyclohexan-1-ol 
• 54307-74-3 (R)-5-methyl-cyclohex-2-enone 
• 283603-57-6 (3S,5R)-3,5-Dimethyl-cyclohexanol 
• 75-24-1 trimethylaluminum 
• 7214-50-8 5-methylcyclohex-2-en-1-one 
• 41248-61-7 1-hydroxy-3r,5c-dimethyl-cyclohexane-ξ-carbonitrile 
• 75-16-1 methylmagnesium bromide 

Downstream Products

• 41248-61-7 1-hydroxy-3r,5c-dimethyl-cyclohexane-ξ-carbonitrile 
• 767-13-5 (+/-)-1r,3t-Dimethyl-cyclohexanol-⁽⁵⁾ 
• 71364-95-9 cis-3,5-Dimethylcyclohexanone oxime 
• 344460-82-8 2-Cyano-((3R,5S)-3,5-dimethyl-cyclohexylidene)-acetic acid ethyl ester 
• 767-13-5 3,5-dimethylcyclohexanol 
• 76993-50-5 1ξ.1'ξ'-Dihydroxy-3r.5c.3'r'.5'c'-tetramethyl-bicyclohexyl 
• 105661-80-1 (2R,4R)-4-((3R,5S)-3,5-Dimethyl-cyclohex-1-enyloxy)-pentan-2-ol 
• 105601-77-2 (2R,4R)-4-((3S,5R)-3,5-Dimethyl-cyclohex-1-enyloxy)-pentan-2-ol 
• 121360-34-7 Acetic acid (1R,3R)-3-((3R,5S)-3,5-dimethyl-cyclohex-1-enyloxy)-1-methyl-butyl ester 
• 121360-34-7 Acetic acid (1R,3R)-3-((3S,5R)-3,5-dimethyl-cyclohex-1-enyloxy)-1-methyl-butyl ester 
• 723732-37-4 1α,3α,5α-(1-aminomethyl)-(3,5-dimethylcyclohexane)acetic acid 

Relevant articles and documents

SYNTHESIS OF HALICHONDRINS

The present invention provides methods for the synthesis of ketones involving a Ni/Zr-mediated coupling reaction. The Ni/Zr-mediated ketolization reactions can be used in the synthesis of halichondrins (e.g., halichondrin A, B, C; homohalichondrin A, B, C; norhalichondnn A, B, C), and analogs thereof. Therefore, the present invention also provides synthetic methods useful for the synthesis of halichondrins, and analogs thereof. Also provided herein are compounds (i.e., intermediates) useful in the synthesis of halichondrins, and analogs thereof. In particular, the present invention provides methods and compounds useful in the synthesis of compound of Formula (H3-A)

A Scalable Synthesis of (R,R)-2,6-Dimethyldihydro-2H-pyran-4(3H)-one

A scalable synthesis of (R,R)-2,6-dimethyldihydro-2H-pyran-4(3H)-one is reported. Key to this strategy is the Ti(OiPr)4-catalyzed Kulinkovich cyclopropanation of silyl protected (R)-ethyl 3-hydroxybutanoate, and subsequent oxidative fragmentati

Kinetic resolution of chiral cyclohex-2-enones by rhodium(I)/binap- catalyzed 1,2- and 1,4-additions

The feasibility of kinetic resolutions of racemic monosubstituted cyclohex-2-enones by Rh/binap-catalyzed reactions was investigated. 1,2-Addition of AlMe3 to the 5-substituted derivatives furnished allylic alcohols in the matched case, while t