72379-99-8

Basic information

• Product Name: bis-(1-phenyl-propylidene)-hydrazine
• Synonyms: bis-(1-phenyl-propylidene)-hydrazine
• CAS NO: 72379-99-8
• Molecular Weight: 264.37
• Mol File: 72379-99-8.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: bis-(1-phenyl-propylidene)-hydrazine(CAS DataBase Reference)
• NIST Chemistry Reference: bis-(1-phenyl-propylidene)-hydrazine(72379-99-8)
• EPA Substance Registry System: bis-(1-phenyl-propylidene)-hydrazine(72379-99-8)

Safety Data

• Hazardous Substances Data: 72379-99-8(Hazardous Substances Data)

Upstream product

• 17336-66-2 propiophenone N-tosylhydrazone 
• 2157-50-8 propiophenone oxime 
• 29076-84-4 propiophenone-imine 
• 52686-70-1 triethylamine-1-(2-naphthylethyl)borane 
• 75-05-8 acetonitrile 
• 85046-72-6 N-[1-Methyl-prop-(E)-ylidene]-N'-[1-phenyl-prop-(E)-ylidene]-hydrazine 
• 85046-73-7 N-Eth-(Z)-ylidene-N'-[1-phenyl-prop-(E)-ylidene]-hydrazine 
• 107-12-0 propiononitrile 
• 93-55-0 1-phenyl-propan-1-one 

Downstream Products

• 85229-38-5 1,1'-Dichlor-1,1'-diphenyl-1,1'-azopropan 
• 1530-03-6 1,1-diphenylpropane 
• 34835-98-8 1-phenyl-1-p-tolyl-propane 
• 37446-36-9 1-phenyl-11-(2,5-dimethylphenyl)propane 
• 38443-18-4 (E)-3,4-diphenylhex-3-ene 
• 85229-43-2 1,1'-Dipivaloxy-1,1'-diphenyl-1,1'-azopropan 
• 85229-42-1 1,1'-Diisobutoxy-1,1'-diphenyl-1,1'-azopropan 
• 85229-41-0 1,1'-Dibutoxy-1,1'-diphenyl-1,1'-azopropan 
• 85229-40-9 1,1'-Dipropionoxy-1,1'-diphenyl-1,1'-azopropan 
• 85229-39-6 1,1'-Diformoxy-1,1'-diphenyl-1,1'-azopropan 
• 82761-17-9 1,1'-Diacetoxy-1,1'-diphenyl-1,1'-azopropan 
• 2941-20-0 1-phenylpropylamine 
• 93-55-0 1-phenyl-propan-1-one 
• 3314-13-4 (1-phenyl-propyl)-hydrazine 

Relevant articles and documents

Cp*Co(iii)-catalyzed annulation of azines by C-H/N-N bond activation for the synthesis of isoquinolines

Herein, an efficient, atom economic and external oxidant free approach has been disclosed for the synthesis of isoquinolines. Azines were employed for annulation reactions with alkynes via sequential C-H/N-N bond activation using an air-stable cobalt catalyst. The method takes advantage of the incorporation of both the nitrogen atoms of azines into the desired isoquinoline products, offering the highest atom economy. In addition, the developed protocol works under external oxidant as well as silver salt free conditions. Furthermore, the established methodology features a relatively broad substrate scope with high product yields and scalability up to the gram level.

Rh-catalyzed sequential oxidative C-H and N-N bond activation: Conversion of azines into isoquinolines with air at room temperature

A rhodium-catalyzed sequential oxidative C-H annulation reaction between ketazines and internal alkynes has been developed via C-H and N-N bond activation with air as an external oxidant, which led to an efficient approach toward isoquinolines with high atom efficiency at rt. Utilizing the distinctive reactivity of this catalysis, both N-atoms of the azines could be efficiently incorporated to the desired isoquinolines under very robust and mild reaction conditions.

Copper-catalyzed N-N bond formation by homocoupling of ketoximes via n-o bond cleavage: Facile, mild, and efficient synthesis of azines

A facile, mild, and efficient copper-catalyzed homocoupling of ketoximes involving N-O bond cleavage in the presence of sodium bisulfite (NaHSO has been developed. This reaction shows good functional group tolerance and affords a broad scope of azines in high yields.