72492-12-7 Usage
Description
Spizofurone, also known by the brand name Maon, is an antiulcer agent that functions by enhancing mucus secretion and improving microcirculation in the gastric mucosa. Additionally, it exhibits an inhibitory effect on acid secretion, making it a valuable compound for treating ulcers and related gastrointestinal issues.
Uses
Used in Pharmaceutical Industry:
Spizofurone is used as an antiulcer agent for its ability to increase mucus secretion and microcirculation in the gastric mucosa, as well as its inhibitory effect on acid secretion. This makes it a beneficial treatment option for individuals suffering from ulcers and other gastrointestinal conditions.
Used in Gastrointestinal Health:
Spizofurone is used to support gastrointestinal health by promoting the protective functions of the stomach lining through increased mucus secretion and improved microcirculation. Its ability to inhibit acid secretion also contributes to its effectiveness in managing and preventing ulcers and other gastric issues.
Originator
Takeda (Japan)
Check Digit Verification of cas no
The CAS Registry Mumber 72492-12-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,2,4,9 and 2 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 72492-12:
(7*7)+(6*2)+(5*4)+(4*9)+(3*2)+(2*1)+(1*2)=127
127 % 10 = 7
So 72492-12-7 is a valid CAS Registry Number.
InChI:InChI=1/C12H10O3/c1-7(13)8-2-3-10-9(6-8)11(14)12(15-10)4-5-12/h2-3,6H,4-5H2,1H3
72492-12-7Relevant articles and documents
Spirocyclopropane compounds. III. Synthesis of spiro[benzofuran-2(3H),1'-cyclopropan]-3-ones for evaluation of gastric antisecretory and antiulcer agents
Kawada,Watanabe,Okamoto,Sugihara,Hirata,Maki,Imada,Sanno
, p. 3532 - 3550 (2007/10/02)
Spiro[benzofuran-2(3H),1'-cyclopropan]-3-one (VI-1) and its derivatives (VI-2 - VI-75) were synthesized in the same manner as described previously for the synthesis of spiro[cyclopropane-1,2'-[2H]indol]-3'(1'H)-ones (I). These spiro[benzofuran-2(3H),1'-cy
Spirobenzofuranone compounds
-
, (2008/06/13)
Novel spirobenzofuranone compounds of the formula: STR1 have gastric secretion inhibitive, antiinflammatory and analgesic activities, and are of value as drugs.
