72653-47-5

Basic information

• Product Name: Benzene, [(1-chlorobutyl)thio]-
• CAS NO: 72653-47-5
• Molecular Formula: C10H13ClS
• Molecular Weight: 200.732
• Mol File: 72653-47-5.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: Benzene, [(1-chlorobutyl)thio]-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, [(1-chlorobutyl)thio]-(72653-47-5)
• EPA Substance Registry System: Benzene, [(1-chlorobutyl)thio]-(72653-47-5)

Safety Data

• Hazardous Substances Data: 72653-47-5(Hazardous Substances Data)

Upstream product

• 930-69-8 sodium thiophenolate 
• 1126-80-3 (n-butylthio)benzene 

Downstream Products

• 133188-88-2 3-((1-Phenylthio)butyl)-cyclohexanone 
• 59919-12-9 1-Phenyl-2-phenylthiopentan-1-one 
• 1638-22-8 4-n-butylphenol 
• 3180-09-4 ortho-butylphenol 
• 6483-60-9 2-Butyl-4,6-dimethyl-phenol 
• 17269-95-3 4-Butyl-2-methylphenol 
• 17269-96-4 butylhydroxytoluene 
• 105473-15-2 (1R,2S)-1-Phenyl-2-phenylsulfanyl-pentan-1-ol 

Relevant articles and documents

Thioalkylation of Enolates, III. Stereoselective Synthesis of Steroids and Related Compounds, II. α-Thioalkylation of Zinc Dienolates to 4-Substituted 1-tert-Butoxy-7a-methyl-hexahydroinden-5-ones

α-Alkylation of the α,β-unsaturated ketone 1 at C-4 has been achieved by thioalkylation of the corresponding zinc dienolate with α-chlorosulfides of type 2.The desulfurization of the β-(phenylthio)ketones 4 leads directly to the 4-substituted hexahydroind

Thioalkylation of Enolates, II. α-Thioalkylation of Zinc Enolates to α,α-Disubstituted Ketones

An α-alkylation of the 2-methylcycloalkanones 1 and 4 at the higher substituted carbon can be achieved by thioalkylation of the corresponding zinc enolates with the α-chlorosulfides 3.The desulfurization can be carried out with either Raney nickel or lithium in diethylamine for compounds which contain double or triple bonds. Key Words: Zinc enolates, thioalkylation of / Ketones, α,α-disubstituted / Desulfurization

A New Syntethic Route to Vinyl Sulfides Utilizing the Reaction of (Phenylthio)carbenes with Nitrile Anions

Reactions of nitrile anion (LiCR2R3CN) and (phenylthio)carbenes generated from 1-chloroalkyl phenyl sulfides (R1CH(Cl)SPh) 2a-e by the action of n-BuLi have been shown to be a useful synthetic route to vinyl sulfides (PhSC(R1)=CR2R3) 3a-k (34-91percent).The nucleophilic attack of the nitrile anion on the carbenic species gave the presumed intermediate β-(phenylthio)-β-lithionitrile, which eliminated LiCN to give the expected vinyl sulfides.The application of the present reaction to the synthesis of cyclic vinyl sulfides was successful: the decomposition of the dianion ofω,ω-bis(phenylthio)alkanenitriles (8b, 8c, 11, and 14) affording the corresponding 1-(phenylthio)cycloalkenes (9, 10, 12, and 15) in 12-87percent yields.