72707-66-5Relevant articles and documents
Artificial [FeFe]-hydrogenase: On resin modification of an amino acid to anchor a hexacarbonyldiiron cluster in a peptide framework
Roy, Souvik,Shinde, Sandip,Hamilton, G. Alexander,Hartnett, Hilairy E.,Jones, Anne K.
experimental part, p. 1050 - 1055 (2011/06/10)
A general method for immobilization of synthetic analogues of the [FeFe]-hydrogenase in designed peptides via on resin modification of an amino acid side chain with a dithiol functional group is described. Utilizing a unique amine side chain as anchor, the dithiol unit is coupled to the peptide via formation of an amide. This dithiol unit precisely positions the two required sulfur atoms for the formation of a [(μ-SRS){Fe-(CO)3} 2] cluster on reaction with [Fe3(CO)12]. UV/Vis and FTIR spectroscopy demonstrate formation of the desired complex.
Radiochemical 18F-fluoroarylation of unsaturated α-, β- and γ-amino acids, application to a radiolabelled analogue of baclofen
H?fling, Sarah B.,Hultsch, Christina,Wester, Hans-Jürgen,Heinrich, Markus R.
experimental part, p. 11846 - 11851 (2009/04/06)
Unsaturated α-, β- and γ-amino acids have been investigated as substrates for the reductive Meerwein arylation. Radical reactions of this type have been shown to be a valuable tool for the fast and efficient introduction of the 4-[18F]fluorophenyl group into precursor molecules allowing short-time syntheses of potential PET radiotracers, which would be more difficult to access by other methods.
Amino acid, derivatives, processes for their preparation and their therapeutic application
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, (2008/06/13)
New amino acid derivatives, processes for their preparation and their therapeutic application. Amino acid derivatives corresponding to the general formulae STR1 These derivatives may be used as medicaments which exhibit an enkephalinase-inhibitory activity.
