72997-55-8Relevant articles and documents
Programmed synthesis of arylthiazoles through sequential C-H couplings
Tani, Satoshi,Uehara, Takahiro N.,Yamaguchi, Junichiro,Itami, Kenichiro
, p. 123 - 135 (2014/01/06)
A programmed synthesis of privileged arylthiazoles via sequential C-H couplings catalyzed by palladium or nickel catalysts has been accomplished. This versatile protocol can supply all possible arylthiazole substitution patterns (2-aryl, 4-aryl, 5-aryl, 2
Palladium-catalyzed C-H functionalization of heteroarenes with aryl bromides and chlorides
Tamba, Shunsuke,Okubo, Youhei,Tanaka, Shota,Monguchi, Daiki,Mori, Atsunori
supporting information; experimental part, p. 6998 - 7001 (2010/11/24)
Palladium-catalyzed C-H arylation of electron-enriched heteroarenes with aryl bromides and aryl chlorides proceeds in the presence of LiO-t-Bu as a base. The reaction allows one-pot synthesis of differently substituted 2,5-diarylthiazole with the same catalyst system by switching the solvent and the amount of base.
Thionation using fluorous Lawesson's reagent
Kaleta, Zoltan,Makowski, Brian T.,Soos, Tibor,Dembinski, Roman
, p. 1625 - 1628 (2007/10/03)
Thionation of amides, 1,4-diketones, N-(2-oxoalkyl)amides, N,N-acylhydrazines, and acyl-protected uridines with the use of a fluorous analogue of the Lawesson's reagent leads to thioamides, thiophenes, 1,3-thiazoles, 1,3,4-thiadiazoles, and acyl-protected 4-thiouridines. The isolation of the final products in high yields is achieved in most cases by a simple filtration (fluorous solid-phase extraction).
