7314-44-5 Usage
Description
2,4-Dimethoxybenzyl alcohol is an organic compound characterized by its colorless to light yellow liquid appearance. It is known for its chemical reactivity, particularly with trifluoroacetic acid, which allows it to yield calix[4]resorcinarene octamethyl ether. 2,4-Dimethoxybenzyl alcohol can then be further processed through demethylation and acetylation to produce the derived octa-acetate.
Uses
Used in Pharmaceutical Industry:
2,4-Dimethoxybenzyl alcohol is used as a medical intermediate for the synthesis of various pharmaceutical compounds. Its ability to react with different reagents and form new compounds makes it a valuable component in the development of drugs with specific therapeutic properties.
Used in Chemical Synthesis:
In the field of chemical synthesis, 2,4-Dimethoxybenzyl alcohol serves as a versatile building block for creating a range of organic compounds. Its reactivity with trifluoroacetic acid and subsequent conversion to calix[4]resorcinarene octamethyl ether and the derived octa-acetate highlights its potential in synthesizing complex molecules for various applications.
Used in Research and Development:
2,4-Dimethoxybenzyl alcohol is also utilized in research and development settings, where its unique chemical properties are explored for potential applications in creating new materials, improving existing compounds, and understanding the underlying chemical reactions involved in their formation.
Check Digit Verification of cas no
The CAS Registry Mumber 7314-44-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,3,1 and 4 respectively; the second part has 2 digits, 4 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 7314-44:
(6*7)+(5*3)+(4*1)+(3*4)+(2*4)+(1*4)=85
85 % 10 = 5
So 7314-44-5 is a valid CAS Registry Number.
InChI:InChI=1/C9H12O3/c1-11-8-4-3-7(6-10)9(5-8)12-2/h3-5,10H,6H2,1-2H3
7314-44-5Relevant articles and documents
High yield synthesis of the parent C-unsubstituted calix[4]resorcinarene octamethyl ether
Falana, Olusegun M.,Al-Farhan, Emile,Keehn, Philip M.,Stevenson, Robert
, p. 65 - 68 (1994)
Treatment of 2,4-dimethoxybenzyl alcohol with trifluoroacetic acid (TFA, 5% in CHCl3) affords, in almost quantitative yield calix[4]resorcinarene octamethyl ether, which on demethylation and acetylation yields the derived octa-acetate.
Synthesis of acyclic and cyclic phosphonates based on substituted 2-hydroxybenzylic alcohols
Brel, V. K.,Mikulenkova, E. A.,Mironov, V. F.,Tatarinov, D. A.,Terekhova, N. V.
, p. 2147 - 2152 (2020/12/09)
A convenient synthesis of benzylic phosphonates and 2,3-dihydrobenzo[d][1,2]oxaphosphole 2-oxides substituted at the aromatic ring, as well as their precursors, 2-hydroxybenzylic alcohols, from the derivatives of salicylic aldehyde, salicylic acid, and 2-hydroxyacetophenone bearing an additional hydroxy or methoxy group at the para position of the aromatic ring was developed. For the first time, the possibility of selective demethylation of the methoxy group positioned ortho to the methylene phosphonate fragment with retention of the methoxy group at the para position was shown.
Cobalt complex catalyzed atom-economical synthesis of quinoxaline, quinoline and 2-alkylaminoquinoline derivatives
Shee, Sujan,Ganguli, Kasturi,Jana, Kalipada,Kundu, Sabuj
supporting information, p. 6883 - 6886 (2018/06/26)
A new phosphine-free Co(ii) complex-catalyzed synthesis of various quinoxalines via dehydrogenative coupling of vicinal diols with both o-phenylenediamines and 2-nitroanilines is reported. This complex was also effective for the synthesis of quinolines. The practical aspect of this catalytic system was revealed by the one-pot synthesis of 2-alkylaminoquinolines.