73397-12-3 Usage
Description
6-Chloro-9-nitro-5-oxo-5H-benzo[a]phenoxazine, also known as CNOB, is a novel prodrug enzyme used in cancer chemotherapy. It is a chemical compound with a unique structure that allows it to be activated by specific enzymes in the body, making it a targeted approach to cancer treatment.
Uses
Used in Cancer Chemotherapy:
6-Chloro-9-nitro-5-oxo-5H-benzo[a]phenoxazine is used as a prodrug enzyme in cancer chemotherapy for its targeted approach to cancer treatment. It is activated by specific enzymes in the body, allowing for selective destruction of cancer cells while minimizing damage to healthy cells.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 6-chloro-9-nitro-5-oxo-5H-benzo[a]phenoxazine is used as a key component in the development of new cancer drugs. Its unique properties make it a promising candidate for the creation of targeted therapies that can improve patient outcomes and reduce side effects associated with traditional chemotherapy.
Used in Research and Development:
6-Chloro-9-nitro-5-oxo-5H-benzo[a]phenoxazine is also used in research and development for the study of enzyme activity and the development of new prodrug enzymes. Its unique mechanism of action provides valuable insights into the field of cancer treatment and the potential for targeted therapies.
Check Digit Verification of cas no
The CAS Registry Mumber 73397-12-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,3,3,9 and 7 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 73397-12:
(7*7)+(6*3)+(5*3)+(4*9)+(3*7)+(2*1)+(1*2)=143
143 % 10 = 3
So 73397-12-3 is a valid CAS Registry Number.
InChI:InChI=1/C16H7ClN2O4/c17-13-15(20)10-4-2-1-3-9(10)14-16(13)23-12-7-8(19(21)22)5-6-11(12)18-14/h1-7H
73397-12-3Relevant articles and documents
Novel phenoxazinone derivatives as enzyme substrates and use thereof as indicator in the detection of microorganisms with peptidase activity
-
, (2008/06/13)
The present invention relates to novel enzymatic substrates with the following general formula: where R1, R2, R3, R4, R5, R6, A and X are as defined in claim 1, the reaction media comprising the same and the use thereof for the detection and/or identification and/or quantification of microorganisms expressing at least one peptidase activity.
Quinone Chemistry. Reaction of 2,3-Dichloro-1,4-naphthoquinone with 2-Aminophenols in Pyridine
Agarwal, Nand L.,Schaefer, Wolfram
, p. 5144 - 5149 (2007/10/02)
The reaction of 2,3-dichloro-1,4-naphthoquinone (1) and 2-aminophenols (2) in pyridine furnished substituted 6-chloro-5H-benzophenoxazin-5-one (10), 5H-benzophenoxazin-5-one (8), 5H-benzophenoxazin-5-one-6-pyridinium chloride (6), 2-(2-hydroxyanilino)-1,4-naphthoquinone-3-pyridinium chloride (5), and 12H-benzophenoxazine-6,11-dione (7).It was observed that the nature and yields of the reaction products were greatly influenced by the substituent present in 2.The reaction mechanism for the formation of all products is discussed, and spectroscopic data are also given.This reaction for the first time led to a development of a novel, convenient synthesis of a new class of heterocyclic quinones (7).
