73466-14-5

Basic information

• Product Name: (7E,9E,11Z,14Z)-(5S,6R)-6-[2-(4-Amino-4-carboxy-butyrylamino)-2-(carboxymethyl-carbamoyl)-ethylsulfanyl]-5-hydroxy-icosa-7,9,11,14-tetraenoic acid
• CAS NO: 73466-14-5
• Molecular Weight: 625.784
• Mol File: 73466-14-5.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: (7E,9E,11Z,14Z)-(5S,6R)-6-[2-(4-Amino-4-carboxy-butyrylamino)-2-(carboxymethyl-carbamoyl)-ethylsulfanyl]-5-hydroxy-icosa-7,9,11,14-tetraenoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (7E,9E,11Z,14Z)-(5S,6R)-6-[2-(4-Amino-4-carboxy-butyrylamino)-2-(carboxymethyl-carbamoyl)-ethylsulfanyl]-5-hydroxy-icosa-7,9,11,14-tetraenoic acid(73466-14-5)
• EPA Substance Registry System: (7E,9E,11Z,14Z)-(5S,6R)-6-[2-(4-Amino-4-carboxy-butyrylamino)-2-(carboxymethyl-carbamoyl)-ethylsulfanyl]-5-hydroxy-icosa-7,9,11,14-tetraenoic acid(73466-14-5)

Safety Data

• Hazardous Substances Data: 73466-14-5(Hazardous Substances Data)

Upstream product

• 102906-05-8 (Z)-6-((R)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-hex-5-enoic acid 
• 102906-18-3 (E)-6-((R)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-hex-5-enoic acid 
• 78377-37-4 7,8-O-isopropylidene-7(R),8-dihydroxyoct-5-enoic acid 
• 82430-34-0 7,8-O-isopropylidene-7(R),8-dihydroxyoct-5-enoic acid 
• 73958-01-7 9-oxo-5,6-trans-epoxynon-7(E)-enoate 
• 73958-10-8 (7E,9E,11Z,14Z)-(5S,6R)-6-[2-(4-Amino-4-carboxy-butyrylamino)-2-(carboxymethyl-carbamoyl)-ethylsulfanyl]-5-hydroxy-icosa-7,9,11,14-tetraenoic acid methyl ester 
• 72297-14-4 5,6-oxido-7,9,11,14-eicosa-pentaenoate 
• 72345-92-7 rac-trans-(1E,3E,5Z,8Z)-(1,3,5,8-tetradecatetraenyl)oxiranebutanoic acid methyl ester 
• 72297-14-4 (+/-)trans-5,6-oxido-7,9-E-11,14-Z-eicosatetraenoic acid methyl ester 
• 73958-09-5 Phosphorane of (Z)-3-nonen-1-yl-triphenylphosponium bromide 
• 73958-01-7 methyl 8-formyl-5(S),6(S)-oxido-7(E)-octenoate 
• 73958-10-8 (7E,9E,11Z,14Z)-(5S,6R)-6-[2-(4-Amino-4-carboxy-butyrylamino)-2-(carboxymethyl-carbamoyl)-ethylsulfanyl]-5-hydroxy-icosa-7,9,11,14-tetraenoic acid methyl ester 
• 75415-33-7 (7E,9E,11Z,14Z)-(5S,6R)-5-Hydroxy-6-{2-(methoxycarbonylmethyl-carbamoyl)-2-[4-methoxycarbonyl-4-(2,2,2-trifluoro-acetylamino)-butyrylamino]-ethylsulfanyl}-icosa-7,9,11,14-tetraenoic acid methyl ester 
• 75415-33-7 (7E,9E,11Z,14Z)-5-Hydroxy-6-{2-(methoxycarbonylmethyl-carbamoyl)-2-[4-methoxycarbonyl-4-(2,2,2-trifluoro-acetylamino)-butyrylamino]-ethylsulfanyl}-icosa-7,9,11,14-tetraenoic acid methyl ester 

Downstream Products

• 76485-14-8 Leukotriene C4 sulfone 
• 70578-51-7 6-trans-Leukotriene B₄ 
• 70578-51-7 (5S,12S)-6-trans-leukotriene B 

Relevant articles and documents

Biomimetic synthesis of leukotriene A

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SYNTHESIS OF LEUKOTRIENES - NEW SYNTHESIS OF NATURAL LEUKOTRIENE A4

The acetonides of D- or L-glyceraldehyde are chiral synthons for an efficient and versatile synthesis of the natural leukotrienes A4, C4, D4 and E4 and equally can be used to prepare the corresponding unnatural analogues.

Stereospecific total synthesis of a 'slow reacting substance' of anaphylaxis, leukotriene C-1

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