73501-02-7Relevant articles and documents
Nitrile Sulphides. Part 1. 1,3-Dipolar Cycloaddition to Carbonyl Groups activated by Trihaloalkyl Substituents; Synthesis and Crystal Structure of 1,3,4-Oxathiazoles
Damas, A. Margarida,Gould, Robert O.,Harding, Marjorie M.,Paton, R. Michael,Ross, John F.,Crosby, John
, p. 2991 - 2996 (2007/10/02)
Nitrile sulphides, generated by the thermal decarboxylation of 1,3,4-oxathiazol-2-ones, undergo 1,3-dipolar cycloaddition to the carbonyl group in chloral, hexachloroacetone and α,α,α-trifluoroacetophenone to yield 2,2,5-trisubstituted 1,3,4-oxathiazoles (18 - 76percent).Characterisation of the products is based on analytical and spectroscopic evidence, and is confirmed for 5-phenyl-2-trichloromethyl-1,3,4-oxathiazole and 5-(p-methoxyphenyl)-2-phenyl-2-trifluoromethyl-1,3,4-oxathiazole by X-ray crystal structure analyses.The oxathiazole rings are planar, with a localised C=N double bond.