73875-21-5Relevant articles and documents
A large scale formal synthesis of CoQ10: Highly stereoselective friedel-crafts allylation reaction of tetramethoxytoluene with (E)-4-chloro-2-methyl-1-phenylsulfonyl-2-butene in the presence of montmorillonite K-10
Lee, Sang Who,Lee, Hee Bong,Kim, Bong Chan,Sadaiah, Kadivendi,Lee, Kyuwoong,Shin, Hyunik
, p. 1257 - 1259 (2013/07/28)
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The Friedel-Crafts allylation of a prenyl group stabilized by a sulfone moiety: Expeditious syntheses of ubiquinones and menaquinones
Min, Jae-Hong,Lee, Jun-Sup,Yang, Jae-Deuk,Koo, Sangho
, p. 7925 - 7927 (2007/10/03)
An efficient synthetic method for the protected p-hydroquinone compounds 4 containing the C5 trans allylic sulfone moiety has been developed by the direct Friedel-Crafts allylation of the protected dihydroquinone 2 with 4-chloro-2-methyl-1-phenylsulfonyl-2-butene (7a) or 4-hydroxy-2-methyl-1-phenylsulfonyl-2-butene (7b). Expeditious total syntheses of coenzyme Q-10 and vitamin K2(20) have been demonstrated from these valuable key compounds 4a and 4b.