73875-22-6

Basic information

• Product Name: (E)-1-(benzenesulfonyl)-4-[3,4-dimethoxy-2,5-bis(methoxymethoxy)-6-methylphenyl]-2-methylbut-2-ene
• Synonyms: (E)-1-(benzenesulfonyl)-4-[3,4-dimethoxy-2,5-bis(methoxymethoxy)-6-methylphenyl]-2-methylbut-2-ene
• CAS NO: 73875-22-6
• Molecular Weight: 480.579
• Mol File: 73875-22-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (E)-1-(benzenesulfonyl)-4-[3,4-dimethoxy-2,5-bis(methoxymethoxy)-6-methylphenyl]-2-methylbut-2-ene(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-1-(benzenesulfonyl)-4-[3,4-dimethoxy-2,5-bis(methoxymethoxy)-6-methylphenyl]-2-methylbut-2-ene(73875-22-6)
• EPA Substance Registry System: (E)-1-(benzenesulfonyl)-4-[3,4-dimethoxy-2,5-bis(methoxymethoxy)-6-methylphenyl]-2-methylbut-2-ene(73875-22-6)

Safety Data

• Hazardous Substances Data: 73875-22-6(Hazardous Substances Data)

Upstream product

• 59277-17-7 1-(benzenesulfonyl)-2-methyl-4-chloro-2-butene 
• 98-09-9 benzenesulfonyl chloride 
• 78-79-5 isoprene 
• 109-87-5 Dimethoxymethane 
• 1092067-54-3 (E)-6-[4-(benzenesulfonyl)-3-methylbut-2-enyl]-2,3-dimethoxy-5-methylbenzene-1,4-diol 
• 73875-21-5 (2'E)-1-(3'-methyl-4'-phenylsulfonylbut-2'-enyl)-6-methyl-2,3,4,5-tetramethoxybenzene 
• 34407-31-3 1-bromo-3,4-dimethoxy-2,5-bis(methoxymethoxy)-6-methylbenzene 

Downstream Products

• 74813-93-7 4-(benzenesulfonyl)-3,7,11,15,19,23,27,31,35,39-decamethyl-1-[3,4-dimethoxy-2,5-bis(methoxymethoxy)-6-methylphenyl]tetraconta-2,6,10,14,18,22,26,30,34,38-decaene 
• 303-98-0 ubidecarenone 
• 64634-91-9 1-[(2E,6E,10E,14E,18E,22E,26E,30E,34E)-3,7,11,15,19,23,27,31,35,39-decamethyltetraconta-2,6,10,14,18,22,26,30,34,38-decaen-1-yl]-3,4-dimethoxy-2,5-bis(methoxymethoxy)-6-methylbenzene 

Relevant articles and documents

Synthesis of coenzyme Q10

A practical synthesis of coenzyme Q10 has been developed. The route features an improved Friedel-Crafts allylation of tetramethoxytoluene with a para-chlorobenzenesulfonyl-substituted C5 allylic chloride at 40 °C. Replacement of the methyl ether protecting groups of the para-hydroquinone by methoxymethyl groups at Q1 stage proceeded efficiently, and allowed the facile final oxidation to coenzyme Q10 to occur under mild acidic conditions. The overall yield of coenzyme Q 10 from commercially available tetramethoxytoluene reached 53 % in this improved procedure. An improved synthesis gave CoQ10 in 53 % overall yield from tetramethoxytoluene through Friedel-Crafts allylation with a para-chlorobenzenesulfonyl-substituted C5 allylic chloride and a modified oxidation procedure. Copyright