74002-22-5

Basic information

• Product Name: cyclopentaniMine
• Synonyms: cyclopentaniMine
• CAS NO: 74002-22-5
• Molecular Formula: C5H9N
• Molecular Weight: 83.13166
• Mol File: 74002-22-5.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: cyclopentaniMine(CAS DataBase Reference)
• NIST Chemistry Reference: cyclopentaniMine(74002-22-5)
• EPA Substance Registry System: cyclopentaniMine(74002-22-5)

Safety Data

• Hazardous Substances Data: 74002-22-5(Hazardous Substances Data)

Usage

Description

Cyclopentanimine, derived from Cyclopentanone, is an organic compound that serves as a key intermediate in the synthesis of various organic compounds. It is characterized by its unique chemical structure and reactivity, making it a versatile building block in the chemical industry.

Uses

Used in Pharmaceutical Industry:
Cyclopentanimine is used as a synthetic intermediate for the development of peptidase IV inhibitors, which are crucial in the treatment of type 2 diabetes. Its role in the synthesis of these inhibitors is significant, as it contributes to the modulation of glucose levels in the body, thus managing and controlling diabetes.
Used in Chemical Synthesis:
In the chemical industry, Cyclopentanimine is utilized as a building block for the synthesis of a wide range of simple and complex organic compounds. Its unique reactivity and structure make it a valuable component in the creation of various chemical products, contributing to the diversity and innovation within the industry.

Upstream product

• 1192-28-5 Cyclopentanone oxime 
• 132407-55-7 N-chloro-1-amino-1-cyclopentanecarboxylic acid 
• 7664-41-7 ammonia 
• 120-92-3 cyclopentanone 
• 55611-39-7 n-allylcyclopentylamine 
• 49830-37-7 1-amino-1-cyanocyclopentane 
• 6407-38-1 butyl-cyclopentyliden-amine 

Downstream Products

• 1003-03-8 Cyclopentamine 
• 111968-95-7 N-<1-(phenylthio)cyclopentyl>acetamide 

Relevant articles and documents

Modulating: Trans -imination and hydrogenation towards the highly selective production of primary diamines from dialdehydes

Bio-based primary diamines are important building blocks for sustainable bio-polymers, but their synthesis remains challenging due to the high susceptibility to polymerization. Herein, we have developed a new strategy to suppress the polymerization by employing a more nucleophilic alkylamine to scavenge the dialdehyde and a Co/ZrO2 catalyst to regulate the trans-imination and hydrogenation activity. With this strategy, 2,5-bis(aminomethyl)furan (BAMF), a promising monomer for the production of new polyamides and polyureas, is successfully synthesized via the reductive amination of biomass-derived 2,5-diformylfuran (DFF) under a H2 and NH3 atmosphere with an unprecedentedly high selectivity up to 95%. This strategy is applicable to the reductive amination of other biomass-derived dialdehydes, thus paving a new way to bio-based diamine monomers. This journal is

Kinetics and mechanism of decomposition of N-chloroamino acids. II: Conformationally restricted models

The kinetics of decomposition of the following conformationally restricted N-chloro-α-amino acids were studied: 1-amino-1-cyclopentanecarboxylic acid (2), 1-amino-1-cyclohexanecarboxylic acid (4), 2-amino-2-norbornanecarboxylic acid (6), and 2-amino-2-benzonorbornanecarboxylic acid (8). The first-order rate constants obtained were 0.520, 5.197, 0.198, and 0.078, respectively, which correlated with the ring strain in the structurally related cyclic ketones cyclopentanone, cyclohexanone, norborane-2-one, and benzonorbornane-2-one. The data are supportive of a concerted mechanism for the decomposition reaction involving an imine-like transition state.