74074-24-1

Basic information

• Product Name: N-(Bis-methylsulfanyl-methylene)-4-nitro-benzamide
• Synonyms: N-(Bis-methylsulfanyl-methylene)-4-nitro-benzamide
• CAS NO: 74074-24-1
• Molecular Weight: 270.333
• Mol File: 74074-24-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: N-(Bis-methylsulfanyl-methylene)-4-nitro-benzamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(Bis-methylsulfanyl-methylene)-4-nitro-benzamide(74074-24-1)
• EPA Substance Registry System: N-(Bis-methylsulfanyl-methylene)-4-nitro-benzamide(74074-24-1)

Safety Data

• Hazardous Substances Data: 74074-24-1(Hazardous Substances Data)

Upstream product

• 619-80-7 4-nitrobenzamide 
• 75-15-0 carbon disulfide 
• 74-88-4 methyl iodide 
• 74-93-1 methylthiol 
• 333-20-0 potassium thioacyanate 
• 122-04-3 4-nitro-benzoyl chloride 
• 90964-35-5 (4-nitro-benzoyl)-dithiocarbamic acid methyl ester 

Downstream Products

• 74074-30-9 2-methyl-3-(4-nitrobenzoyl)-1-phenylisothiourea 
• 57295-48-4 5-methylsulfanyl-3-(4-nitro-phenyl)-1H-[1,2,4]triazole 
• 74-93-1 methylthiol 
• 88735-97-1 N-[2-[3-Ethyl-3H-benzothiazol-(2E)-ylidene]-1-methylsulfanyl-eth-(E)-ylidene]-4-nitro-benzamide 
• 107166-56-3 2-[(E)-4-Nitro-benzoylimino]-5-oxo-hexahydro-pyrimidine-4-carboxylic acid ethyl ester 
• 107166-41-6 [2-Methyl-3-(4-nitro-benzoyl)-isothioureido]-acetic acid ethyl ester 
• 62812-80-0 N-(4,5-dihydro-thiazol-2-yl)-4-nitro-benzamide 

Relevant articles and documents

Reaction Behaviour of Amides with Carbondisulphide and Isothiocyanates

Reactions of substituted arylamides, hetarylamides and furylacrylicamide 1 with carbon disulphide present a possibility to synthesize imino-dithiocarbonic-S,S'-diester 5.The mechanism of the reaction and the reaction conditions are investigated.Quantum chemical investigations by simple HMO-method in connection with the experimental results describe the reaction in dependence upon the influence of substituent in 2- and 4-position to the phenylring.Further more is describe the reaction of amide with isothiocyanates to thiourea 6 and isothiourea 7. The structures of the final products are determined by analytical dates.

Reactions with N-Acylimino-dithiocarbonic-acid-diesters

Reactions of N-acylimino-dithiocarbonic-acid-S,S-diesters 1 with nucleophilic compounds present new possibilities to synthesize heterocycles.With amines 1a reacts by mono- and disubstitution, respectively, of methylthio-groups to isothioureas 2 and guanidines 3, with 1,2-binucleophilic arenes to benzoheterocycles 4, with aliphatic diamines to imidazolines 5, pyrimidines 6, diazepines 7 and the hexamethylene-diamine-derivatives 8. 1a reacts also with hydrazines to 1,2,4-triazoles 9 and with hydrazides to the thiosemicarbazones 10 or 1,3,4-oxadiazoles 11.Heterocyclisations of 1 with guanidines, thiourea, salts of thiourea and amidines give the 1,3,5-triazines 12, 14, 15 and 16.N-benzoyl-dithiocarbonic-acid-methylester -amid reacts with CH-acidic compounds to thiazoles 17.The structures of the final products are determined by i.r.-, 1H-n.m.r.-, u.v.- and mass-spectras.