7421-23-0

Basic information

• Product Name: MK-2
• Synonyms: MK-2;2-[(E)-3,7-Dimethyl-2,6-octadienyl]-3-methyl-1,4-naphthalenedione;2-Methyl-3-[(2E)-3,7-dimethyl-2,6-octadienyl]-1,4-naphthoquinone;Menaquinone 2;Vitamin K2(10);Vitamin MK-2;ANTI-MAPKAPK2 antibody produced in mouse
• CAS NO: 7421-23-0
• Molecular Formula: C₂₁H₂₄O₂
• Molecular Weight: 308.41406
• Mol File: 7421-23-0.mol
• Article Data: 1

Chemical Properties

• Melting Point: 52-53 °C(Solv: acetone (67-64-1); ethanol (64-17-5))
• Boiling Point: 448.6±45.0 °C(Predicted)
• Appearance: /
• Density: 1.045±0.06 g/cm3(Predicted)
• Storage Temp.: -20°C
• CAS DataBase Reference: MK-2(CAS DataBase Reference)
• NIST Chemistry Reference: MK-2(7421-23-0)
• EPA Substance Registry System: MK-2(7421-23-0)

Safety Data

• Hazardous Substances Data: 7421-23-0(Hazardous Substances Data)

Upstream product

• 6138-90-5 trans-geranyl bromide 
• 64648-85-7 2-Bromo-3-Methyl-1,1,4,4-tetramethoxy-1,4-dihydronaphthalene 

Downstream Products

• 34185-71-2 3-(5-carboxy-3-methyl-(2E)-penten-1-yl)-2-methyl-1,4-naphthoquinone 

Relevant articles and documents

Organocopper Chemistry of Quinone Bisketals. Application to the Synthaais of Isoprenoid Quinone Systems

The reactions of organocuprates of 1,4-benzoquinone and 1,4-naphthoquinone bisketals are reported.These reagents, formed from the corresponding lithium reagent, cuprous iodide, and dimethyl sulfide react efficiently with allylic bromides (allyl, prenyl, geranyl, and phytyl), often with utilization of greater than one R group of the R2CuLi.Their reactions with acid chlorides and benzyl bromide proceed with acceptable efficiency, but they are unreactive toward a number of other substrates.The utility of this chemistry in the synthesis of menaquinone-2, phylloquinone,cymopol, and cymopol methyl ether is described.