7425-63-0 Usage
Description
Methyl Bromopyruvate, also known as MBP, is an organic compound that serves as an inhibitor of carbonic anhydrase. It is characterized by its ability to inhibit the enzyme carbonic anhydrase, which plays a crucial role in various physiological processes.
Uses
Used in Pharmaceutical Industry:
Methyl Bromopyruvate is used as an inhibitor for carbonic anhydrase due to its ability to block the enzyme's activity. This inhibition can be beneficial in the development of drugs targeting conditions where carbonic anhydrase plays a role, such as glaucoma, epilepsy, and altitude sickness.
Used in Chemical Synthesis:
Methyl Bromopyruvate is used as a synthetic intermediate for the production of various compounds. For instance, it has been utilized in the synthesis of 2-(4-amino-4-carboxybutyl)thiazole-4-carboxylic acid and methyl-1-(bromomethyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-1-carboxylate. These synthesized compounds can have potential applications in the development of new drugs and pharmaceuticals.
Check Digit Verification of cas no
The CAS Registry Mumber 7425-63-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,4,2 and 5 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 7425-63:
(6*7)+(5*4)+(4*2)+(3*5)+(2*6)+(1*3)=100
100 % 10 = 0
So 7425-63-0 is a valid CAS Registry Number.
InChI:InChI=1/C4H5BrO3/c1-8-4(7)3(6)2-5/h2H2,1H3
7425-63-0Relevant articles and documents
EFFICIENT AND SCALABLE SYSTHESIS OF 2-(1'H-INDOLE-3'-CARBONYL)-THIAZOLE-4-CARBOXYLIC ACID METHYL ESTER AND ITS STRUCTURAL ANALOGS
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Page/Page column 25, (2016/06/01)
Methods of synthesizing 2-(1'H-indole-3'-carbonyl)-thiazole-4-carboxylic acid methyl ester (ITE) and structural analogs thereof. The methods include condensation reactions or condensation and oxidation reactions to form the thiazoline or thiazole moiety of ITE or its structural analogs.
PROPYL 3-BROMO-2-OXOPROPIONATE AND DERIVATIVES AS NOVEL ANTICANCER AGENTS
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Page/Page column 58, (2008/06/13)
The present invention is directed to compositions that inhibit glycolysis, preferentially in cancer. Specifically, the anticancer compositions comprise 3-halo-2-oxopropionate and its derivatives, such as ester derivatives. However, in specific embodiments, the anticancer composition is sodium 3-halo-2-oxopropionate, such as sodium 3-bromo-2--oxopropionate and a stabilizing agent, such as carbonic acid. In particular embodiments, the compositions of the present invention further comprise a metabolic intermediate for normal cells to utilize in a pathway for an alternate energy source, thereby providing protection to normal cells. In other embodiments, the 3-halo-2-oxopropionate or its ester derivative is used in combination with an additional cancer therapy, such as radiation and/or a drug.