74311-50-5

Basic information

• Product Name: (R)-1-diphenylthiophosphinyl-2-(dimethylaminomethyl)ferrocene
• CAS NO: 74311-50-5
• Molecular Weight: 459.375
• Mol File: 74311-50-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (R)-1-diphenylthiophosphinyl-2-(dimethylaminomethyl)ferrocene(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-1-diphenylthiophosphinyl-2-(dimethylaminomethyl)ferrocene(74311-50-5)
• EPA Substance Registry System: (R)-1-diphenylthiophosphinyl-2-(dimethylaminomethyl)ferrocene(74311-50-5)

Safety Data

• Hazardous Substances Data: 74311-50-5(Hazardous Substances Data)

Upstream product

• 7704-34-9 sulfur 
• 74311-52-7 [2-(N,N-dimethylaminomethyl)ferrocenyl]diphenylphosphine sulfide 
• 10544-50-0 sulfur 

Downstream Products

• 896465-43-3 (S)-1-diphenylthiophosphinyl-2-(acetoxymethyl)ferrocene 
• 74311-51-6 (Spl)-2-(1-N,N-dimethylaminomethyl)-1-diphenylphosphinoferrocene 
• 61116-64-1 (R)-1-diphenylphosphino-2-(dimethylaminomethyl)ferrocene 
• 74311-50-5 (R)-[2-(N,N-dimethylaminomethyl)ferrocenyl]diphenylphosphine sulfide 
• 74311-52-7 (R)-1-diphenylthiophosphinyl-2-(dimethylaminomethyl)ferrocene 
• 541540-61-8 (R)-[2-(N,N-dimethylaminomethyl)ferrocenyl]diphenylphosphine oxide 
• 1144039-26-8 (2-formylferrocenyl)diphenylphosphine oxide 
• 854497-26-0 trimethyl[(2-diphenylthiophosphinyl)ferrocenylmethyl]ammonium iodide 

Relevant articles and documents

Synthesis and catalytic applications of new chiral ferrocenyl P,O ligands

A new method to synthesize both enantiomers of 2-diphenylphosphino-ferrocenecarboxaldehyde with the phosphine group protected as a thiophosphine group was developed. These aldehydes react with 1,2 or 1,3 diols to give, in good yields, new chiral phosphine-acetals. For unsymmetrical (R)-1,3-butanediol, the new asymmetrical acetalic carbon is asymmetric and its configuration was completely controlled by the chirality of the diol. These new P,O ligands were tested in the palladium-catalyzed asymmetric allylic substitution of 1,3-diphenylprop-2-enylacetate. Good yields and enantioselectivities up to 77% were observed. The catalytic performances of two diastereoisomeric ligands with opposite configurations in planar chirality only proved to be significantly different, showing a strong influence of both planar and central chiralities.