7432-10-2

Basic information

• Product Name: 1-Methyl-2,5-(2-hydroxytrimethylene)pyrrolidine
• Synonyms: 1-Methyl-2,5-(2-hydroxytrimethylene)pyrrolidine;3-Hydroxytropan;Pseudotropinone;Tropan-3-ol
• CAS NO: 7432-10-2
• Molecular Formula: C₈H₁₅NO
• Molecular Weight: 141.21
• Product Categories: Heterocycles;Miscellaneous Reagents
• Mol File: 7432-10-2.mol
• Article Data: 6

Chemical Properties

• Melting Point: 63-64°C
• Appearance: /
• Storage Temp.: Refrigerator
• CAS DataBase Reference: 1-Methyl-2,5-(2-hydroxytrimethylene)pyrrolidine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Methyl-2,5-(2-hydroxytrimethylene)pyrrolidine(7432-10-2)
• EPA Substance Registry System: 1-Methyl-2,5-(2-hydroxytrimethylene)pyrrolidine(7432-10-2)

Safety Data

• Hazardous Substances Data: 7432-10-2(Hazardous Substances Data)

Usage

Description

1-Methyl-2,5-(2-hydroxytrimethylene)pyrrolidine, also known as Glycerol, is a simple polyol compound that is a colorless, odorless, viscous liquid. It is a versatile organic molecule with a hydroxyl group attached to each carbon atom. Glycerol is widely used in various industries due to its unique properties, such as its ability to form hydrogen bonds and its compatibility with water and organic solvents.

Uses

Used in Pharmaceutical Industry:
1-Methyl-2,5-(2-hydroxytrimethylene)pyrrolidine is used as a pharmaceutical agent for its various therapeutic applications. It serves as a humectant, helping to retain moisture in the body and prevent dehydration. Additionally, it is used in the formulation of suppositories, elixirs, and expectorants due to its solubility in water and ability to dissolve other substances.
Used in Cosmetics and Personal Care Industry:
In the cosmetics and personal care industry, 1-Methyl-2,5-(2-hydroxytrimethylene)pyrrolidine is used as a moisturizing agent, solvent, and preservative. Its humectant properties make it an ideal ingredient in skincare products, hair care products, and toothpaste, helping to maintain hydration and improve the texture of the products.
Used in Food and Beverage Industry:
1-Methyl-2,5-(2-hydroxytrimethylene)pyrrolidine is used as a humectant, emulsifier, and sweetener in the food and beverage industry. It helps to retain moisture in products, improve texture, and extend shelf life. Glycerol is commonly found in confectionery, baked goods, and soft drinks, as well as in the production of e-liquids for electronic cigarettes.
Used in Industrial Applications:
In industrial applications, 1-Methyl-2,5-(2-hydroxytrimethylene)pyrrolidine is used as a raw material for the production of various chemicals, such as glycerol esters, glycerol ethers, and polyglycerols. It is also used in the manufacturing of explosives, as a component in the production of nitroglycerin and other nitrate esters.
Used in Energy Production:
1-Methyl-2,5-(2-hydroxytrimethylene)pyrrolidine is used as a feedstock for the production of biofuels, such as biodiesel and bio-jet fuel. Its compatibility with various chemical processes makes it a valuable resource in the development of sustainable and renewable energy sources.
Used in Research and Development:
In the field of research and development, 1-Methyl-2,5-(2-hydroxytrimethylene)pyrrolidine is used as a reagent and solvent in various chemical reactions and processes. Its versatility and compatibility with a wide range of substances make it an essential component in the synthesis of new compounds and materials.

Upstream product

• 532-24-1 tropinone 
• 500-55-0 apoatropine 
• 51-55-8 atropine 
• 4540-25-4 fillalbin 
• 120-29-6 3-tropanol 
• 510-25-8 (+/-)-1-phenyl-1,2,3,4-tetrahydro-naphthalene-1r,4t-dicarboxylic acid di-tropane-3endo-yl ester 

Downstream Products

• 3423-27-6 3-endo-8-methyl-8-azabicyclo[3.3.1]octan-3-ol acetate 
• 532-24-1 tropinone 
• 135-97-7 pseudotropine 
• 538-09-0 nortropine 
• 51-55-8 atropine 
• 144-62-7 oxalic acid 
• 74-89-5 methylamine 
• 156143-26-9 (S)-(+)-tropan-3-yl 2-(4'-bromophenyl)propionate 
• 156143-26-9 (R)-(-)-tropanyl 2-(4'-bromophenyl)propionate 
• 1379513-74-2 8-methyl-8-azabicyclo[3.2.1]octan-3-yl 2-(tert-butoxycarbonylamino)-2-phenylacetate 
• 143557-91-9 (1R,3S,5S)-tert-butyl 3-hydroxy-8-azabicyclo[3.2.1]octane-8-carboxylate 

Relevant articles and documents

“Inverse” Frustrated Lewis Pairs: An Inverse FLP Approach to the Catalytic Metal Free Hydrogenation of Ketones

For the first time have boron-containing weak Lewis acids been demonstrated to be active components of Frustrated Lewis Pair (FLP) catalysts in the hydrogenation of ketones to alcohols. Combining the organosuperbase (pyrr)3P=NtBu with the Lewis acid 9-(4-CF3-C6H4)-BBN generated an “inverse” FLP catalyst capable of hydrogenating a range of aliphatic and aromatic ketones including N-, O- and S-functionalized substrates and bio-mass derived ethyl levulinate. Initial computational and experimental studies indicate the mechanism of catalytic hydrogenation with “inverse” FLPs to be different from conventional FLP catalysts that contain strong Lewis acids such as B(C6F5)3.

Oxidation of a anticholinergic drug atropine sulfate monohydrate by alkaline copper(III) periodate complex: A kinetic and mechanistic study

The oxidation of a anticholinergic drug, Atropine sulfate monohydrate (ASM) by diperiodatocuprate( III) (DPC) has been investigated spectrophotometrically in aqueous alkaline medium at a constant ionic strength of 0.50mol dm -3. The reaction between diperiodatocuprate(III) and atropine sulfate exhibits 1 : 2 stoichiometry (atropine sulfate : diperiodatocuprate(III)). The main oxidation products were identified and confirmed by spectral studies including IR, 1H NMR and GC-MS. A suitable mechanism is proposed. The order with respect to diperiodatocuprate(III) concentration was unity, while the order with respect to atropine sulfate concentration was less than unity over the concentration range studied. The rates increased with an increase in alkali concentration and decreased with an increase in periodate concentration. The activation parameters with respect to slow step of the mechanism were calculated and the thermodynamic quantities were also determined. Kinetic experiments suggest that [Cu(OH)2(H3IO6)]- is the reactive species of copper(III). by Oldenbourg Wissenschaftsverlag, Muenchen.

ALKALOIDS OF Convolvulus subhirsutus

The total alkaloids of the roots of Convolvulus subhirsutus collected in the period of vigorous growth close to the village of Dzhilga, Chimkent province, have been studied.From the phenolic fraction of the total alkaloids of this species of plant we have isolated phyllalbine and convolidine for the first time.From the nonphenolic fraction of the combined bases we isolated convolvine, which has been found previously, the new alkaloid confoline, and an unidentified base (III).On the basis of spectral characteristics and some spectral transformations it has been established that confoline has the structure of (+)-N-formylconvolvine.