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743460-16-4

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743460-16-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 743460-16-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,4,3,4,6 and 0 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 743460-16:
(8*7)+(7*4)+(6*3)+(5*4)+(4*6)+(3*0)+(2*1)+(1*6)=154
154 % 10 = 4
So 743460-16-4 is a valid CAS Registry Number.

743460-16-4Downstream Products

743460-16-4Relevant articles and documents

Discovery of muscarinic acetylcholine receptor antagonist and beta 2 adrenoceptor agonist (MABA) dual pharmacology molecules

Hughes, Adam D.,Chin, Kay H.,Dunham, Sarah L.,Jasper, Jeffrey R.,King, Kristin E.,Lee, Tae Weon,Mammen, Mathai,Martin, Jerri,Steinfeld, Tod

, p. 1354 - 1358 (2011/04/16)

We sought to design dual pharmacology bronchodilators targeting both the M3 muscarinic acetylcholine and beta-2 adrenergic (β2) receptors by applying our multivalent approach to drug discovery. Herein, we describe our initial discovery and the SAR of the first such compounds with matched potencies at both receptors.

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