743460-49-3 Usage
Description
Biphenyl-2-ylcarbamic acid 1-[2-((benzyloxycarbonyl)-N-methylamino)ethyl]piperidin-4-yl ester is a complex organic compound that serves as a crucial intermediate in the synthesis of pharmaceuticals. It is characterized by its unique molecular structure, which includes a biphenyl-2-ylcarbamic acid core, a piperidin-4-yl ester group, and a benzyloxycarbonyl-N-methylaminoethyl moiety. biphenyl-2-ylcarbamic acid 1-[2-((benzyloxycarbonyl)-N-methylamino)ethyl]piperidin-4-yl ester plays a significant role in the development of new drugs for the treatment of various diseases.
Uses
Used in Pharmaceutical Industry:
Biphenyl-2-ylcarbamic acid 1-[2-((benzyloxycarbonyl)-N-methylamino)ethyl]piperidin-4-yl ester is used as an intermediate in the synthesis of Des-4''(methylpiperidine-4-carboxamide)-4''-hydroxymethyl Revefenacin (D119860), an impurity of Revefenacin (R279600). Revefenacin is a pharmaceutical drug used for the treatment of chronic obstructive pulmonary diseases (COPD). biphenyl-2-ylcarbamic acid 1-[2-((benzyloxycarbonyl)-N-methylamino)ethyl]piperidin-4-yl ester's role in the synthesis process is essential for the development of effective treatments for this respiratory condition.
In the pharmaceutical industry, biphenyl-2-ylcarbamic acid 1-[2-((benzyloxycarbonyl)-N-methylamino)ethyl]piperidin-4-yl ester is utilized for its potential to contribute to the creation of new drug candidates. Its unique structure allows for the exploration of various chemical modifications, which can lead to the discovery of novel therapeutic agents with improved efficacy and safety profiles. biphenyl-2-ylcarbamic acid 1-[2-((benzyloxycarbonyl)-N-methylamino)ethyl]piperidin-4-yl ester's involvement in the synthesis of Revefenacin highlights its importance in the development of treatments for chronic obstructive pulmonary diseases, a significant health concern worldwide.
Check Digit Verification of cas no
The CAS Registry Mumber 743460-49-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,4,3,4,6 and 0 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 743460-49:
(8*7)+(7*4)+(6*3)+(5*4)+(4*6)+(3*0)+(2*4)+(1*9)=163
163 % 10 = 3
So 743460-49-3 is a valid CAS Registry Number.
743460-49-3Relevant articles and documents
Preparation methods of revefenacin intermediate and revefenacin
-
Paragraph 0073-0075, (2021/05/26)
The invention relates to a synthesis method of a revefenacin intermediate, which specifically comprises the following steps: in a solvent, enabling piperidin-4-yl [1,1-biphenyl]-2-carbamate to react with methyl(2-oxyethyl) tert-butyl carbamate in the pres
PROCESS FOR PREPARING A BIPHENYL-2-YLCARBAMIC ACID
-
, (2012/02/01)
The invention provides a process of preparing an intermediate useful in the synthesis of biphenyl-2-ylcarbamic acid 1-(2-{[4-(4-carbamoylpiperidin-1-ylmethyl)benzoyl]methylamino}ethyl)piperidin-4-yl ester, and a process of preparing a crystalline freebase of the ester.
