74420-00-1

Basic information

• Product Name: 1,7-DIDEAZAADENINE
• Synonyms: 1,7-DIDEAZAADENINE;1H-PYRROLO[2,3-B]PYRIDIN-4-AMINE;4-AMINO-1H-PYRROLO[2,3-B]PYRIDINE;4-AMINO-7-AZAINDOLE;4-AMINO-7-AZAINDOLE HYDROCHLORIDE;4-AMINO-7-AZAINDOLE/4-Amino-1H-pyrrolo[2,3-b]pyridine;1H-pyrrolo[2,3-b]pyridin-4-aMine hydrochloride
• CAS NO: 74420-00-1
• Molecular Formula: C₇H₇N₃
• Molecular Weight: 133.15
• Product Categories: Heterocycle-Pyridine series;Pyrrolidines ,Pyrroles
• Mol File: 74420-00-1.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 348.6±35.0 °C(Predicted)
• Appearance: /
• Density: 1.367 g/cm³
• Refractive Index: 1.78
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• Solubility: DMSO (Slightly), Methanol (Slightly)
• PKA: 8.28±0.20(Predicted)
• CAS DataBase Reference: 1,7-DIDEAZAADENINE(CAS DataBase Reference)
• NIST Chemistry Reference: 1,7-DIDEAZAADENINE(74420-00-1)
• EPA Substance Registry System: 1,7-DIDEAZAADENINE(74420-00-1)

Safety Data

• Hazard Codes: Xi
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 74420-00-1(Hazardous Substances Data)

Usage

Description

1,7-DIDEAZAADENINE, also known as 1H-Pyrrolo[2,3-b]pyridin-4-amine, is an organic compound with the chemical formula C6H6N4. It is a tan solid and is used in the preparation of pyrrolotriazines, which are a class of compounds with potential applications in various fields.

Uses

Used in Pharmaceutical Industry:
1,7-DIDEAZAADENINE is used as a key intermediate for the synthesis of pyrrolotriazines, which are compounds with potential therapeutic applications. These pyrrolotriazines may exhibit various biological activities, such as anti-cancer, anti-inflammatory, or anti-microbial properties, making them valuable in the development of new drugs.
Used in Chemical Research:
1,7-DIDEAZAADENINE can also be utilized in chemical research as a starting material for the development of novel compounds with specific properties. Its unique structure allows for further functionalization and modification, enabling the creation of new molecules with potential applications in various industries, such as materials science, agriculture, or environmental science.

InChI:InChI=1/C7H7N3/c8-6-2-4-10-7-5(6)1-3-9-7/h1-4H,(H3,8,9,10)

Upstream product

• 55052-28-3 4-chloro-7-azaindole 

Downstream Products

• 688782-67-4 benzyl 3-(2-amino-6-{[3-fluoro-4-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)phenyl]amino}-pyrimidin-4-yl)piperidine-1-carboxylate 
• 688781-37-5 N₄-[3-fluoro-4-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)phenyl]-6-piperidin-3-ylpyrimidine-2,4-diamine 
• 688781-75-1 3-fluoro-4-((1H-pyrrolo [2,3-b]pyridin-4-yl)oxy)aniline 
• 1454838-76-6 2,6-dichloro-N-(1H-pyrrolo[2,3-b]pyridin-4-yl)benzamide 
• 55052-28-3 4-chloro-7-azaindole 
• 173897-93-3 (R)-N-(1H-pyrrolo[2,3-b]pyridin-4-yl)-4-(1-benzyloxycarbonylaminoethyl)benzamide 
• 74420-02-3 1H-pyrrolo<2,3-b>pyridin-4-ol (1,7-Dideazahypoxanthine) 
• 640735-23-5 4-fluoro-1H-pyrrolo[2,3-b]pyridine 

Relevant articles and documents

Concise and Efficient Synthesis of 4-Fluoro-1H-pyrrolo[2,3-b]pyridine

(Equation presented) Two routes describing the preparation of 4-fluoro-1H-pyrrolo[2,3-b]pyridine (4a) from 1H-pyrrolo[2,3-b]pyridine N-oxide (1) are presented. Regioselective fluorination was achieved using either the Balz-Schiemann reaction or lithium-halogen exchange.