7448-87-5

Basic information

• Product Name: 2-Propen-1-one, 1-(4-chlorophenyl)-
• CAS NO: 7448-87-5
• Molecular Formula: C9H7ClO
• Molecular Weight: 166.607
• Mol File: 7448-87-5.mol
• Article Data: 50

Chemical Properties

• Melting Point: 172 °C
• Boiling Point: 81-83 °C(Press: 0.04 Torr)
• Density: 1.188 g/cm3
• CAS DataBase Reference: 2-Propen-1-one, 1-(4-chlorophenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propen-1-one, 1-(4-chlorophenyl)-(7448-87-5)
• EPA Substance Registry System: 2-Propen-1-one, 1-(4-chlorophenyl)-(7448-87-5)

Safety Data

• Hazardous Substances Data: 7448-87-5(Hazardous Substances Data)

Upstream product

• 50-00-0 formaldehyd 
• 1777-56-6 4-chlorobenzoylmethylenetriphenylphosphorane 
• 637-87-6 1-Chloro-4-iodobenzene 
• 201230-82-2 carbon monoxide 
• 6285-05-8 4'-chloropropiophenone 
• 106119-12-4 4-morpholinyl p-chlorophenyl sulfide 
• 67-56-1 methanol 
• 99-91-2 para-chloroacetophenone 
• 67-68-5 dimethyl sulfoxide 
• 75-11-6 diiodomethane 
• 38488-19-6 1-(4-chlorophenyl)-2-(phenylsulfonyl)ethanone 
• 1474048-86-6 1-(4-chlorophenyl)-3-(phenylselanyl)propan-1-one 
• 104-88-1 4-chlorobenzaldehyde 
• 58824-54-7 p-chlorophenylvinylcarbinol 

Downstream Products

• 75910-29-1 1-(4-chlorophenyl)-3-tosylpropan-1-one 
• 53842-12-9 1-(p-chlorophenyl)-1,4-pentanedione 
• 138174-25-1 1-(4-Chloro-phenyl)-hex-5-en-1-one 
• 120312-68-7 1-(4'-chlorophenyl)-4-(4''-methylphenyl)-butane-1,4-dione 
• 1260083-24-6 (E)-1-(4-chlorophenyl)-6-(3-methyl-1H-indol-2-yl)hex-2-en-1-one 
• 1256284-91-9 1-(4-chlorophenyl)-2-(9-methyl-2,3,4,9-tetrahydro-1H-carbazol-4-yl)ethanone 
• 1307917-13-0 1-(4-chloro-phenyl)-5-methyl-4-[1-(4-tosyl)-pyrrolidin-2-yl]-hex-4-en-1-one 
• 1384176-79-7 C₁₄H₁₅ClO₆ 
• 1384176-88-8 methyl 7-(4-chlorophenyl)-2,3,7-trioxoheptanoate 
• 1384176-71-9 methyl 7-(4-chlorophenyl)-2-diazo-3,7-dioxoheptanoate 
• 1339700-52-5 1-(4'-chlorophenyl)-4,4,4-trifluoro-1-butanone 
• 1529771-22-9 4-chloro-1-(4-chlorophenyl)-4,4-difluorobutan-1-one 
• 1529771-32-1 4-bromo-1-(4-chlorophenyl)-4,4-difluorobutan-1-one 

Relevant articles and documents

Silver oxide(I) promoted Conia-ene/radical cyclization for a straightforward access to furan derivatives

A novel access to fused furan cores using silver oxide(I) has been developed. Mechanistic investigations indicate the involvement of a Conia-ene reaction/radical cyclization for an expedient path to complex furan derivatives. The reaction is broad in scop

Mild Darzens Annulations for the Assembly of Trifluoromethylthiolated (SCF3) Aziridine and Cyclopropane Structures

We report mild new annulation approaches to trisubstituted trifluoromethylthiolated (SCF3) aziridines and cyclopropanes via Darzens inspired protocols. The products of these anionic annulations, rarely studied previously, possess attractive features rendering them valuable building blocks for synthesis platforms. In this study, trisubstituted acetophenone nucleophiles bearing SCF3 and bromine substituents in their α position were shown to undergo [2 + 1] annulations with vinyl ketones and tosyl-protected imines under mild reaction conditions.

Visible-Light-Driven Nitrogen Radical-Catalyzed [3 + 2] Cyclization of Vinylcyclopropanes and N-Tosyl Vinylaziridines with Alkenes

A visible light photoredox-promoted and nitrogen radical catalyzed [3 + 2] cyclization of vinylcyclopropanes and N-tosyl vinylaziridines with alkenes is developed. Key to the success of this process is the use of the readily tunable hydrazone as a nitrogen radical catalyst. Preliminary mechanism studies suggest that the photogenerated nitrogen radical undergoes reversible radical addition to the vinylcyclopropanes and N-tosyl vinylaziridines to enable their ring-opening C-C and C-N bond cleavage and ensuing cyclization with alkenes.