7462-67-1

Basic information

• Product Name: (3-methyl-3-phenyloxiran-2-yl)(phenyl)methanone
• Synonyms: Methanone, (3-methyl-3-phenyloxiranyl)phenyl-, cis-; Methanone, (3-methyl-3-phenyloxiranyl)phenyl-, trans-
• CAS NO: 7462-67-1
• Molecular Formula: C₁₆H₁₄O₂
• Molecular Weight: 238.2812
• Mol File: 7462-67-1.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 372.3°C at 760 mmHg
• Flash Point: 166.7°C
• Density: 1.168g/cm³
• Vapor Pressure: 9.69E-06mmHg at 25°C
• Refractive Index: 1.597
• CAS DataBase Reference: (3-methyl-3-phenyloxiran-2-yl)(phenyl)methanone(CAS DataBase Reference)
• NIST Chemistry Reference: (3-methyl-3-phenyloxiran-2-yl)(phenyl)methanone(7462-67-1)
• EPA Substance Registry System: (3-methyl-3-phenyloxiran-2-yl)(phenyl)methanone(7462-67-1)

Safety Data

• Hazardous Substances Data: 7462-67-1(Hazardous Substances Data)

Usage

General Description

The chemical compound "(3-methyl-3-phenyloxiran-2-yl)(phenyl)methanone" is an organic compound with the molecular formula C17H16O2. It is a ketone with two main groups - the oxiran-2-yl group and the phenyl group. The oxiran-2-yl group consists of a three-membered ring with a methyl and phenyl substituent, while the phenyl group is a six-carbon aromatic ring. (3-methyl-3-phenyloxiran-2-yl)(phenyl)methanone is commonly used in organic synthesis and pharmaceutical research due to its potential for creating new molecules with various functional groups. Additionally, it may have applications in the development of pharmaceuticals, agrochemicals, and materials science.

Upstream product

• 6397-70-2 3-hydroxy-1,3-diphenylbutan-1-one 
• 98-86-2 acetophenone 
• 19804-64-9 trans-(3-methyl-3-phenyloxiran-2-yl)(phenyl)methanone 
• 100-52-7 benzaldehyde 
• 98-83-9 isopropenylbenzene 
• 495-45-4 dypnone 
• 925-93-9 ethyl [2]alcohol 
• 141-52-6 sodium ethanolate 
• 19804-64-9 cis-(3-methyl-3-phenyloxiran-2-yl)(phenyl)methanone 
• 70729-30-5 1,3-Diphenyl-3-chloro-2-hydroxy-1-butanone 
• 54435-79-9 (E)-1,3-diphenyl-3-methyl-2-propen-1-one 
• 64-17-5 ethanol 
• 124-41-4 sodium methylate 
• 66364-97-4 1,3-Diphenyl-3-chloro-2-hydroxy-1-butanone 

Downstream Products

• 19804-64-9 trans-(3-methyl-3-phenyloxiran-2-yl)(phenyl)methanone 
• 70397-72-7 1,2-Diphenyl-2-methyl-1,3-propanedione 
• 70729-30-5 1,3-Diphenyl-3-chloro-2-hydroxy-1-butanone 
• 19804-64-9 cis-(3-methyl-3-phenyloxiran-2-yl)(phenyl)methanone 
• 66364-97-4 1,3-Diphenyl-3-chloro-2-hydroxy-1-butanone 
• 92007-87-9 1,3-Diphenyl-2-hydroxy-3-methoxy-1-butanone 
• 92007-86-8 1,3-Diphenyl-2-hydroxy-3-methoxy-1-butanone 
• 2042-85-5 1,2-diphenylpropan-1-one 
• 91899-75-1 1,3-Diphenyl-1,2-butanedione 
• 5355-62-4 1,3-Diphenyl-butan-1,3-diol 
• 5381-88-4 1,3-Diphenyl-1,2-dihydroxy-butan 
• 102704-17-6 2-phenyl-3-(1-phenyl-ethyl)-quinoxaline 
• 6397-70-2 3-hydroxy-1,3-diphenylbutan-1-one 
• 74097-59-9 (+/-)-(4S,5R)-4,5-dihydro-5-methyl-3,5-diphenyl-1-tosyl-1H-pyrazol-4-ol 

Relevant articles and documents

Highly enantioselective epoxidation of olefins by H2O2 catalyzed by a non-heme Fe(ii) catalyst of a chiral tetradentate ligand

The chiral tetradentate N4-donor ligand, 1-methyl-2-({(S)-2-[(S)-1-(1-methylbenzimidazol-2-yl methyl)pyrrolidin-2-yl]pyrrolidin-1-yl}methyl) benzimidazole (S,S-PDBzL), based on a chiral dipyrrolidine backbone, has been synthesized and its corresponding Fe(ii) complex has been prepared and characterized. The X-ray structure of the complex reveals that the Fe(ii) ion is in a distorted octahedral coordination environment with two cis-oriented coordination sites occupied by (labile) triflate anions. The ability of the iron complex to catalyze asymmetric epoxidation reactions of olefins with H2O2 was investigated, using 2-cyclohexen-1-one, 2-cyclopenten-1-one, cis-β-methylstyrene, isophorone, chalcones and tetralones as substrates. Different carboxylic acids were used as additives to enhance yields and enantioselectivities, and 2-ethylhexanoic acid was found to give the best results. The catalysis results indicate that the Fe(ii) complex is capable of effecting comparatively high enantioselectivities (>80%) in the epoxidation reactions.

Asymmetric epoxidation with H2O2 by manipulating the electronic properties of non-heme iron catalysts

A non-heme iron complex that catalyzes highly enantioselective epoxidation of olefins with H2O2 is described. Improvement of enantiomeric excesses is attained by the use of catalytic amounts of carboxylic acid additives. Electronic effects imposed by the ligand on the iron center are shown to synergistically cooperate with catalytic amounts of carboxylic acids in promoting efficient O-O cleavage and creating highly chemo-and enantioselective epoxidizing species which provide a broad range of epoxides in synthetically valuable yields and short reaction times.

Stereoselective synthesis of 3,5-dialkyl-3,5-dihydro-3,5-diphenyl-4H- pyrazol-4-ones

We report stereoselective five-step syntheses of cis-3-ethyl-3,5-dihydro-3, 5-diphenyl-5-methyl-4H-pyrazol-4-one (cis-1b) and trans-3,5-diethyl-3,5-dihydro- 3,5-diphenyl-4H-pyrazol-4-one (trans-1c). The key synthon was 1,3-diphenylpent-2-en-1-one (5b) synthesized in a new one-pot crossed aldol/dehydration reaction of acetophenone with propiophenone using titanium(IV) chloride/tributylamine, followed by treatment with methanesulfonyl chloride and triethylamine. Georg Thieme Verlag Stuttgart.