74661-16-8 Usage
Description
2-Hydroxydodecanedioic acid is an organic compound that can be found in urine samples from patients undergoing calcium-4-(2,4-dihydroxy-3,3-dimethylbutyramido) butyrate hemihydrate (hopantenate) therapy during episodes of Reye's-like syndrome. It is characterized by the presence of two hydroxyl groups and two carboxylic acid groups in its molecular structure, which may contribute to its potential applications in various fields.
Uses
Used in Pharmaceutical Industry:
2-Hydroxydodecanedioic acid is used as a biomarker for monitoring the effects of hopantenate therapy in patients with Reye's-like syndrome. Its presence in urine samples can help in assessing the therapeutic response and adjusting the treatment accordingly.
Used in Cosmetics and Skincare Industry:
2-Hydroxydodecanedioic acid is used as an active ingredient in the development of treatments for various skin disorders. Its properties make it suitable for addressing issues such as psoriasis, severe dryness, itchiness, stretch marks, acne, and microbial infections. 2-hydroxydodecanedioic acid may contribute to improved skin health and appearance by promoting skin hydration, reducing inflammation, and supporting the skin's natural barrier function.
Check Digit Verification of cas no
The CAS Registry Mumber 74661-16-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,4,6,6 and 1 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 74661-16:
(7*7)+(6*4)+(5*6)+(4*6)+(3*1)+(2*1)+(1*6)=138
138 % 10 = 8
So 74661-16-8 is a valid CAS Registry Number.
InChI:InChI=1/C12H22O5/c13-10(12(16)17)8-6-4-2-1-3-5-7-9-11(14)15/h10,13H,1-9H2,(H,14,15)(H,16,17)
74661-16-8Relevant articles and documents
Enzymatic Oxidative Tandem Decarboxylation of Dioic Acids to Terminal Dienes
Dennig, Alexander,Kurakin, Sara,Kuhn, Miriam,Dordic, Andela,Hall, Mélanie,Faber, Kurt
supporting information, p. 3473 - 3477 (2016/07/29)
The biocatalytic oxidative tandem decarboxylation of C7–C18dicarboxylic acids to terminal C5–C16dienes was catalyzed by the P450 monooxygenase OleT with conversions up to 29 % for 1,11-dodecadiene (0.49 g L–1). The sequential nature of the cascade was proven by the fact that decarboxylation of intermediate C6–C11ω-alkenoic acids and heptanedioic acid exclusively gave nonconjugated 1,4-pentadiene; scale-up allowed the isolation of 1,15-hexadecadiene and 1,11-dodecadiene; the system represents a short and green route to terminal dienes from renewable dicarboxylic acids.
