7473-42-9 Usage
Description
METHYL-2,3,5-TRI-O-BENZOYL-A-D-ARABINOFURANOSIDE is a white solid chemical compound that serves as an important intermediate in the synthesis of various biologically active molecules. It is particularly used in the preparation of 1-αand 1-β-D-Arabinofuranosyl-2-nitroimidazole (α-AZA and β-AZA), which are potential markers for tissue hypoxia.
Uses
Used in Pharmaceutical Industry:
METHYL-2,3,5-TRI-O-BENZOYL-A-D-ARABINOFURANOSIDE is used as a key intermediate in the synthesis of α-AZA and β-AZA, which are potential markers for tissue hypoxia. These markers can be employed in the development of diagnostic tools and therapeutic strategies for conditions associated with tissue hypoxia, such as cancer and cardiovascular diseases.
Used in Research and Development:
In the field of research and development, METHYL-2,3,5-TRI-O-BENZOYL-A-D-ARABINOFURANOSIDE is utilized for the synthesis of novel compounds with potential applications in various areas of medicine and biology. Its unique chemical properties make it a valuable building block for the development of new drugs and diagnostic agents.
Chemical Properties:
METHYL-2,3,5-TRI-O-BENZOYL-A-D-ARABINOFURANOSIDE is a white solid with distinct chemical properties that make it suitable for use in the synthesis of various biologically active molecules. Its structure and reactivity contribute to its versatility in chemical reactions, allowing for the creation of a wide range of compounds with potential applications in the pharmaceutical and biotechnology industries.
Check Digit Verification of cas no
The CAS Registry Mumber 7473-42-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,4,7 and 3 respectively; the second part has 2 digits, 4 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 7473-42:
(6*7)+(5*4)+(4*7)+(3*3)+(2*4)+(1*2)=109
109 % 10 = 9
So 7473-42-9 is a valid CAS Registry Number.
InChI:InChI=1/C27H24O8/c1-31-27-23(35-26(30)20-15-9-4-10-16-20)22(34-25(29)19-13-7-3-8-14-19)21(33-27)17-32-24(28)18-11-5-2-6-12-18/h2-16,21-23,27H,17H2,1H3
7473-42-9Relevant articles and documents
Preparation of the tri-arabino di-mycolate fragment of mycobacterial arabinogalactan from defined synthetic mycolic acids
Mohammed, Mohsin O.,Al Dulayymi, Juma'a R.,Baird, Mark S.
supporting information, p. 36 - 42 (2016/11/25)
An efficient synthetic approach to tri-arabino di-mycolates, using structurally defined synthetic α-, keto and methoxy mycolic acids is described.
Facile synthesis of β- And α-arabinofuranosides and application to cell wall motifs of M. tuberculosis
Thadke, Shivaji A.,Mishra, Bijoyananda,Hotha, Srinivas
supporting information, p. 2466 - 2469 (2013/06/27)
Propargyl 1,2-orthoesters of arabinose are exploited for the synthesis of 1,2-trans furanosides; easily accessible 1,2-trans ribofuranosides are converted to challenging 1,2-cis-arabinofuranosides by oxidoreduction. Utility of these protocols was demonstrated by the successful synthesis of major structural motifs present in the cell surface of Mycobacterium tuberculosis. Key furanosylations were carried out under gold-catalyzed glycosidation conditions.
A one-pot synthesis of 1-α- and 1-β-d-arabinofuranosyl-2- nitroimidazoles: Synthons to the markers of tumor hypoxia
Naimi, Ebrahim,Kumar, Piyush,McEwan, Alexander J. B.,Wiebe, Leonard I.
, p. 173 - 178 (2007/10/03)
1-α- and 1-β-D-Arabinofuranosyl-2-nitroimidazole (α-AZA and β-AZ A) are synthons for a number of potential markers of tissue hypoxia. A one pot synthesis in which 2-nitroimidazole is coupled with a mixture of α-and β-1-O-acetyl-2,3,5-tri-O-benzoyl-D-arabi