74866-37-8

Basic information

• Product Name: [(2-phenyl-2-propenyl)sulfonyl]benzene
• Synonyms: [(2-phenyl-2-propenyl)sulfonyl]benzene
• CAS NO: 74866-37-8
• Molecular Formula: C₁₅H₁₄O₂S
• Molecular Weight: 258.33546
• Mol File: 74866-37-8.mol
• Article Data: 32

Chemical Properties

• Melting Point: 43-45 °C(Solv: ethanol (64-17-5))
• Boiling Point: 450.8±38.0 °C(Predicted)
• Appearance: /
• Density: 1.166±0.06 g/cm3(Predicted)
• CAS DataBase Reference: [(2-phenyl-2-propenyl)sulfonyl]benzene(CAS DataBase Reference)
• NIST Chemistry Reference: [(2-phenyl-2-propenyl)sulfonyl]benzene(74866-37-8)
• EPA Substance Registry System: [(2-phenyl-2-propenyl)sulfonyl]benzene(74866-37-8)

Safety Data

• Hazardous Substances Data: 74866-37-8(Hazardous Substances Data)

Upstream product

• 873-55-2 sodium benzenesulfonate 
• 7757-83-7 sodium sulfite 
• 98-83-9 isopropenylbenzene 
• 80-17-1 benzenesufonyl hydrazide 
• 1193-82-4 racemic methyl phenyl sulfoxide 
• 591-50-4 iodobenzene 
• 5670-65-5 (E)-1-nitro-2-phenyl-1-propene 
• 5155-87-3 3-phenylbut-3-enoic acid 
• 98-09-9 benzenesulfonyl chloride 
• 5670-65-5 1-nitro-2-phenylpropene 
• 3360-53-0 1-bromo-2-phenyl-1-propene 
• 98-86-2 acetophenone 
• 1424999-26-7 4,4,5,5-tetramethyl-2-(3-(phenylsulfonyl)prop-1-en-2-yl)-1,3,2-dioxaborolane 
• 704-80-3 (E)-3-phenyl-2-butenoic acid 

Downstream Products

• 74866-53-8 3-(phenylsulfonyl)-2-phenyl-1-heptene 
• 127159-32-4 1-bromo-2-phenyl-3-phenylsulphonyl-2-propanol 
• 136490-39-6 (3-cyclohexylprop-1-en-2-yl)benzene 

Relevant articles and documents

Photoredox/cobaloxime co-catalyzed allylation of amines and sulfonyl hydrazines with olefins to access α-allylic amines and allylic sulfones

Herein, we reported a dual-catalytic platform for the allylation of amines and sulfonyl hydrazines with olefins to selectively access α-allylic amines and allylic sulfones in good yields by combining photoredox catalysis and cobaloxime catalysis. This strategy avoided the use of a stoichiometric amount of terminal oxidant and the use of pre-functionalized allylic precursors, representing a green and ideal atom- & step-economical process. Good substrate scope and gram-scale synthesis demonstrated the utility of this protocol. Mechanistic studies revealed that a radical process is probably involved in this reaction.

Copper-catalyzed radical oxyallylation of olefins for the construction of alkene-containing isoxazolines

A radical-mediated approach to alkene oxyallylation using allylic oximes is described. The reaction proceeds under copper-catalytic redox-neutral conditions and tolerates various functional groups. This protocol thus enables the synthesis of structurally valuable isoxazolines and the introduction of a versatile olefin motif in a single step.

Controllable Activation of β-Alkyl Nitroalkenes: Regioselective Synthesis of Allyl and Vinyl Sulfones

The regiospecific radical reactions of β-alkyl nitroalkenes with sulfonyl hydrazides depended to a great extent on the choice of a solvent and catalyst. In the presence of dimethylformamide (DMF), β-alkyl nitroalkenes more likely converted into electron-rich allyl nitro compounds, which reacted with sulfonyl hydrazides to afford allyl sulfones with high regioselectivity. While in acetonitrile (CH3CN), vinyl sulfones were obtained directly via sulfonation of electron-deficient β-alkyl nitroalkenes. The mechanism investigation revealed that the regioselectivity was controlled by the equilibrium of β-alkyl nitroalkenes and allyl nitro compounds.