74993-54-7

Basic information

• Product Name: O-(m-chloro-phenyl)-hydroxylamine
• Synonyms: O-(m-chloro-phenyl)-hydroxylamine
• CAS NO: 74993-54-7
• Molecular Weight: 143.573
• Mol File: 74993-54-7.mol
• Article Data: 12

Chemical Properties

• CAS DataBase Reference: O-(m-chloro-phenyl)-hydroxylamine(CAS DataBase Reference)
• NIST Chemistry Reference: O-(m-chloro-phenyl)-hydroxylamine(74993-54-7)
• EPA Substance Registry System: O-(m-chloro-phenyl)-hydroxylamine(74993-54-7)

Safety Data

• Hazardous Substances Data: 74993-54-7(Hazardous Substances Data)

Upstream product

• 63503-60-6 3-chlorophenylboronic acid 
• 1079392-32-7 C₁₄H₈ClNO₃ 
• 625-98-9 3-chlorofluorobenzene 
• 108-43-0 3-monochlorophenol 

Downstream Products

• 889666-80-2 C₄₁H₆₀ClN₃O₁₂ 
• 2985-80-0 4-chloro-2-hydroxybenzophenone 
• 74993-61-6 Benzoic acid 4-chloro-2-hydroxy-phenyl ester 
• 3743-12-2 N-(4-chloro-2-hydroxyphenyl)benzamide 
• 108-43-0 3-monochlorophenol 
• 144181-67-9 N-(4-chloro-2-hydroxyphenyl)-2,2,2-trifluoroacetamide 
• 119431-22-0 N-(2-chloro-4-hydroxyphenyl)trifluoroacetamide 
• 74993-59-2 N-(3-Chloro-phenoxy)-benzamide 
• 17609-80-2 4-amino-3-chlorophenol 
• 56962-00-6 2-amino-3-chlorophenol 
• 28443-50-7 2-amino-5-chlorophenol 

Relevant articles and documents

An Activity-Based Sensing Fluorogenic Probe for Monitoring Ethylene in Living Cells and Plants

Ethylene (ET) is an important gaseous plant hormone. It is highly desirable to develop fluorescent probes for monitoring ethylene in living cells. We report an efficient RhIII-catalysed coupling of N-phenoxyacetamides to ethylene in the presenc

Dual Directing-Groups-Assisted Redox-Neutral Annulation and Ring Opening of N-Aryloxyacetamides with 1-Alkynylcyclobutanols via Rhodium(III)-Catalyzed C-H/C-C Activations

A cascade [3 + 2] annulation and ring opening of N-aryloxyacetamides with 1-alkynylcyclobutanols via Rh(III)-catalyzed redox-neutral C-H/C-C activations using internal oxidative O-NHAc and -OH as the dual directing groups has been achieved. This reaction provided an efficient and regioselective approach to benzofuran derivatives with good functional group compatibility and high yields.

Rh(III)-Catalyzed Redox-Neutral Unsymmetrical C-H Alkylation and Amidation Reactions of N-Phenoxyacetamides

A Rh(III)-catalyzed unsymmetrical C-H alkylation and amidation of N-phenoxyacetamides with diazo compounds has been developed under mild and redox-neutral conditions, producing dinitrogen as the only byproduct. The reaction represents the first example of one-step, unsymmetrical difunctionalization of two ortho-C-H bonds. Experimental and computational studies support that N-phenoxyacetamides most likely undergo an initial ortho-C-H alkylation with diazo compounds via a Rh(III)-catalyzed C-H activation, and the resulting Rh(III) intermediate subsequently undergoes an intramolecular oxidative addition into the O-N bond to form a Rh(V) nitrenoid species that is protonated and further directed toward electrophilic addition to the second ortho position of the phenyl ring. This work might provide a new direction for unsymmetrical C-H difunctionalization reactions in an efficient manner.