75207-64-6

Basic information

• Product Name: (3R,7aα)-Octahydro-7α-acetoxy-3aα-hydroxy-3α-(hydroxymethyl)-1,1,3,5α-tetramethyl-1H-indene-4β-carboxylic acid
• Synonyms: (3R,7aα)-Octahydro-7α-acetoxy-3aα-hydroxy-3α-(hydroxymethyl)-1,1,3,5α-tetramethyl-1H-indene-4β-carboxylic acid;Botryoloic acid
• CAS NO: 75207-64-6
• Molecular Formula: C17H28O6
• Molecular Weight: 328.40062
• Mol File: 75207-64-6.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (3R,7aα)-Octahydro-7α-acetoxy-3aα-hydroxy-3α-(hydroxymethyl)-1,1,3,5α-tetramethyl-1H-indene-4β-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (3R,7aα)-Octahydro-7α-acetoxy-3aα-hydroxy-3α-(hydroxymethyl)-1,1,3,5α-tetramethyl-1H-indene-4β-carboxylic acid(75207-64-6)
• EPA Substance Registry System: (3R,7aα)-Octahydro-7α-acetoxy-3aα-hydroxy-3α-(hydroxymethyl)-1,1,3,5α-tetramethyl-1H-indene-4β-carboxylic acid(75207-64-6)

Safety Data

• Hazardous Substances Data: 75207-64-6(Hazardous Substances Data)

Upstream product

• 52988-64-4 10-oxodihydrobotrydial 
• 54433-86-2 dihydrobotrydial 
• 52988-64-4 Acetic acid (2aR,5aS,8S,8aR,8bS)-8b-hydroxy-1,1,2a,6-tetramethyl-5-oxo-decahydro-4-oxa-acenaphthylen-8-yl ester 

Relevant articles and documents

Chemical transformations on botryane skeleton. Effect on the cytotoxic activity

Eighteen compounds with a botryane skeleton have been obtained through chemical transformations of various toxins from the fungus Botrytis cinerea. During the course of these transformations, the C-10 carbon of the botryane skeleton was found to exhibit an interesting high regioselectivity to oxidizing and reducing agents. In addition, the cytotoxicity of 27 botryane derivatives was determined in vitro against Hs578T, MDA-MB-231, HT-1080, U87-MG, IMR-90, and HUVEC cell lines. The results of this study confirm that the cytotoxicity of botrydial (1) and its derivatives is related to the presence of a 1,5-dialdehyde functionality.