75238-99-2Relevant articles and documents
Reactivity of Heterocyclic Compounds. VI. 2,6-Diaminopyrimidine-5-carbonitriles and 3,5-Dicyanopyridones from 2-Amino-4H-pyran-3,5-dicarbonitriles
Seoane, C.,Soto, J. L.,Quinteiro, M.
, p. 35 - 41 (2007/10/02)
The reaction of different 2-amino-4H-pyrans (1, 10) with guanidine affords 2,6-diaminopyrimidine derivatives (3).Treatment of the pyrans mentioned or their acetylated derivatives with trityl tetrafluoroborate does not yield pyrylium salts, and pyrid-2-one
Synthesis of Heterocyclic Compounds, XXXVII Preparation of 4,6-Diaryl-1,2-dihydro-2-thioxo-3,5-pyridinedicarbonitriles and Related Compounds
Encinas, Maria Jesus Rubio,Seoane, Carlos,Soto, Jose L.
, p. 213 - 222 (2007/10/02)
The reaction of cyanothioacetamide (1) with α-benzoylcinnamonitriles 2 in basic ethanolic solution leads to 4,6-diaryl-1,2-dihydro-2-thioxo-3,5-pyridinedicarbonitriles 3 together with the disulfides 4.Treatment of 4 with 2-mercaptoethanol causes transformation into 3 which can lead to 4 upon reaction with either iodine-potassium iodide or dimethyl sulfoxide-trifluoroacetic acid.Methylation of 3 or 4 yields the expected methylthiopyridines 5.On the other hand, reaction of 3 with methyl chloroacetate allows the preparation of thienopyridines 8.
Ring Transformations of 4H-Pyrans. Pyridines from 2-Amino-4H-Pyrans
Seoane, Carlos,Soto, Jose L.,Zamorano, Pilar,Quinteiro, Margarita
, p. 309 - 314 (2007/10/02)
Ring transformations of 4H-pyrans into pyridines are reported.Treatment of 2-amino-4,6-diaryl-3,5-dicyano-4H-pyrans (I) with nitrosylsulfuric acid brings about their transformation into 3,5-dicyano-4,6-diaryl-2-pyridones (VI) which can also be obtained fr
