753488-72-1Relevant articles and documents
Concise synthesis and structure-activity relationships of combretastatin A-4 analogues, 1-aroylindoles and 3-aroylindoles, as novel classes of potent antitubulin agents
Liou, Jing-Ping,Chang, Yi-Ling,Kuo, Fu-Ming,Chang, Chun-Wei,Tseng, Huan-Yi,Wang, Chiung-Chiu,Yang, Yung-Ning,Chang, Jang-Yang,Lee, Shiow-Ju,Hsieh, Hsing-Pang
, p. 4247 - 4257 (2004)
The synthesis and study of the structure-activity relationships of two new classes of synthetic antitubulin compounds based on 1-aroylindole and 3-aroylindole skeletons are described. Lead compounds 3, 10, and 14 displayed potent cytotoxicities with ICsu