754191-79-2

Basic information

• Product Name: 2-bis(5-methyl-2-furyl)methyl-5-nitrobenzoic acid
• Synonyms: 2-bis(5-methyl-2-furyl)methyl-5-nitrobenzoic acid
• CAS NO: 754191-79-2
• Molecular Weight: 341.32
• Mol File: 754191-79-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-bis(5-methyl-2-furyl)methyl-5-nitrobenzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-bis(5-methyl-2-furyl)methyl-5-nitrobenzoic acid(754191-79-2)
• EPA Substance Registry System: 2-bis(5-methyl-2-furyl)methyl-5-nitrobenzoic acid(754191-79-2)

Safety Data

• Hazardous Substances Data: 754191-79-2(Hazardous Substances Data)

Upstream product

• 610-93-5 6-nitrophthalide 
• 89891-73-6 6-nitro-3-bromo-3H-isobenzofuran-1-one 
• 87-41-2 2-benzofuran-1(3H)-one 
• 534-22-5 2-methylfuran 
• 7464-91-7 2-formyl-5-nitrobenzoic acid 

Relevant articles and documents

Furan ring opening - Isocoumarine ring closure: A recyclization reaction of 2-carboxyaryldifurylmethanes

A general method for the synthesis of isocoumarine derivatives has been developed. Bis(5-R-2-furyl)methylbenzoic acids (R = methyl, ethyl) underwent recyclization and subsequent cyclization into tetracyclic isochromene-1-one derivatives under treatment with hydrogen chloride in methanol. It has been shown that intermediate 4-(5-R-furan-2-yl)-3-(3-oxo-3-R-propyl)-isochromene-1- ones can be obtained selectively by varying a concentration of the hydrogen chloride and reaction times. In the case of R = tert-butyl only corresponding 4-[5-(tert-butyl)-2-furyl]-3-(4,4-dimethyl-3-oxopentyl)-1-isochromenones were isolated regardless of the reaction conditions.