756-09-2Relevant articles and documents
PYRIMIDONE DERIVATIVES AS SELECTIVE CYTOTOXIC AGENTS AGAINST HIV INFECTED CELLS
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Page/Page column 48, (2020/07/14)
The present disclosure is directed to pyrimidone derivatives of Formula I and their use for selectively killing HIV infected GAG-POL expressing cells without concomitant cytotoxicity to HIV nave cells, and for the treatment or prophylaxis of infection by HIV, or for the treatment, prophylaxis or delay in the onset or progression of AIDS or AIDS Related Complex (ARC).
Polyfluoroalkoxy phosphonic and phosphinic acid derivatives: II. Reversible esterase inhibitors
Krutikova,Krutikov,Erkin
experimental part, p. 434 - 439 (2010/08/04)
Polyfluoroalkyl esters of phosphoric, alkylphosphonic and 1-hydroxypolyfluoroalkylphosphonic acids exhibited significant antiesterase activity against various esterases of animal and microbial origin. Moreover, with some compounds reversible inhibition of enzymes was observed due to the specific influence of hydrophobic fragments of the target products.
Method for preparing α-substituted ω-hydroperfluoroalkanes
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, (2008/06/13)
A method for the preparation of α-substituted ω-dihydroperluoroalkane derivatives of the general formula H(CF2 CF2)n R wherein R=H or COOH, and n=1-10 is characterized by oxidizing α, α, ω-trihydroperfluoroalcohols with an oxygen gas or an oxygen-containing gas in the presence of a homogeneous copper catalyst and an alkaline agent in an organic solvent with subsequent isolation of the desired product.