75626-23-2Relevant articles and documents
Synthesis of novel tetrahydroisoquinoline bronchodilators
Dalence-Guzmán, Maria F.,Toftered, J?rgen,Oltner, Viveca Thornqvist,Wensbo, David,Johansson, Martin H.
scheme or table, p. 4999 - 5003 (2010/10/05)
The synthesis and bronchorelaxing effects of a series of novel tetrahydroisoquinoline amides are described. The compounds were evaluated for their ability to relax LTD4 contracted isolated human small airways ex-vivo. Several compounds demonstrated highly
Cephalosporins
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, (2008/06/13)
A syn isomer in (R) or (S) form or a mixture thereof of a compound of the formula STR1 in the form of an internal salt or a non-toxic, pharmaceutically acceptable acid addition salt wherein R1, R2, R3 and R5 are individually defined in the specification, R4 is --OH or alkoxy of 1 to 8 carbon atoms, A and A' are individually selected from the group consisting of hydrogen, an equivalent of an alkali metal or alkaline earth metal, magnesium, ammonium and an organic amine, or one or two of --COOA or --COOA' ARE --CO2 --, the wavy line means --CH2 R6 can be in the E or Z position, R6 in the quaternary ammonium form is selected from the group consisting of STR2 X is defined as in the specification with the proviso that when R3 is --OH or alkoxy of 1 to 8 carbon atoms, at least one R1, R2 and R5 is other than hydrogen having antibacterial properties.