75863-05-7Relevant articles and documents
Chemoselective conjugate addition of dimethylzinc-mediated ether and acetal radicals to alkylidenemalonates and asymmetric reactions
Yamada, Ken-Ichi,Maekawa, Masaru,Akindele, Tito,Nakano, Mayu,Yamamoto, Yasutomo,Tomioka, Kiyoshi
supporting information; experimental part, p. 9535 - 9538 (2009/04/07)
(Chemical Equation Presented) Cyclic and acyclic ether or acetal radicals were generated directly from ethers or acetals by the action of dimethylzinc-air, and their subsequent conjugate addition reaction with alkylidenemalonates afforded the corresponding conjugate adducts in reasonably high yields. The reaction with benzylidenemalonates bearing formyl and imino groups gave chemoselectively the conjugate addition products. The asymmetric reaction of bis(8-phenylmenthyl) benzylidenemalonate proceeded diastereoselectively to provide the adduct with 93:7 dr.