760987-96-0

Basic information

• Product Name: dimethyl 5,5'-[(1E,1'E)-(2-fluoro-1,4-phenylene)bis(ethene-2,1-diyl)]bis(2-methoxybenzoate)
• Synonyms: dimethyl 5,5'-[(1E,1'E)-(2-fluoro-1,4-phenylene)bis(ethene-2,1-diyl)]bis(2-methoxybenzoate)
• CAS NO: 760987-96-0
• Molecular Weight: 476.501
• Mol File: 760987-96-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: dimethyl 5,5'-[(1E,1'E)-(2-fluoro-1,4-phenylene)bis(ethene-2,1-diyl)]bis(2-methoxybenzoate)(CAS DataBase Reference)
• NIST Chemistry Reference: dimethyl 5,5'-[(1E,1'E)-(2-fluoro-1,4-phenylene)bis(ethene-2,1-diyl)]bis(2-methoxybenzoate)(760987-96-0)
• EPA Substance Registry System: dimethyl 5,5'-[(1E,1'E)-(2-fluoro-1,4-phenylene)bis(ethene-2,1-diyl)]bis(2-methoxybenzoate)(760987-96-0)

Safety Data

• Hazardous Substances Data: 760987-96-0(Hazardous Substances Data)

Upstream product

• 62937-75-1 2-fluoro-1,4-divinylbenzene 
• 137000-66-9 1,4-diethynyl-2-fluorobenzene 
• 75676-72-1 2-chloro-4-iodo-1-methoxybenzene 
• 67-56-1 methanol 
• 1379597-71-3 (E,E)-1-fluoro-2,5-bis(3-chloro-4-methoxystyryl)benzene 
• 95-78-3 2,5-Dimethylaniline 
• 69857-33-6 1-fluoro-2,5-bis(bromomethyl)benzene 
• 696-01-5 2-fluoro-1,4-dimethylbenzene 
• 78515-16-9 methyl 5-formyl-2-methoxybenzoate 
• 760987-95-9 [4-(diethoxy-phosphorylmethyl)-2-fluoro-benzyl]-phosphonic acid diethyl ester 

Relevant articles and documents

Acetamidoarenediazonium Salts: Opportunities for Multiple Arene Functionalization

Unlike their ortho counterparts, meta- and para-acetamidoanilines can be converted into the corresponding acetamidoarenediazonium salts. These offer various opportunities for multiple Pd-catalyzed arene functionalization reactions, such as Matsuda-Heck-, Suzuki-Miyaura- or Fujiwara-Moritani couplings. Acetamidoarenediazonium salts, accessible from simple acetamidoanilines, are starting points for multiple Pd-catalyzed arene functionalization reactions.

Fluoro-substituted and 13C-labeled styrylbenzene derivatives for detecting brain amyloid plaques

Two styrylbenzene derivatives, (E,E)-1-fluoro-2,5-bis-(3-hydroxycarbonyl-4- hydroxy)styrylbenzene (FSB) and (E,E)-1-bromo-2,5-bis(3-hydroxycarbonyl-4- hydroxy)styrylbenzene-α,α′-13C2 ([ 13C]BSB), were synthesized for use as a histochemical stain to detect amyloid plaques of Alzheimer's disease (AD) brain sections. An analysis of fluorescence spectra demonstrated that FSB shows approximately twofold fluorescence intensity relative to the conventional styrylbenzene derivative, (E,E)-1-bromo-2,5-bis-(3-hydroxycarbonyl-4-hydroxy)styrylbenzene (BSB). Moreover, FSB was found to stain amyloid plaques and neurofibrillary tangles of AD brains with greater fluorescence intensity and a lower level of background signals compared to BSB. These finding indicate that FSB can be an excellent fluorescent compound to label human amyloid lesions with high sensitivity and specificity. Because of the possession of a nuclide with a quantized angular momentum, both FSB and [13C]BSB are also potential contrast agents for magnetic resonance imaging to locate AD pathologies in vivo.