76166-08-0

Basic information

• Product Name: methyl 15-(tert-butyldimethyl)silyloxy-8(R)-methoxy-11(R)-p-nitrobenzoyloxy-9(S),12(R)-oxy-eicosa-13-ynoate
• Synonyms: methyl 15-(tert-butyldimethyl)silyloxy-8(R)-methoxy-11(R)-p-nitrobenzoyloxy-9(S),12(R)-oxy-eicosa-13-ynoate
• CAS NO: 76166-08-0
• Molecular Weight: 661.909
• Mol File: 76166-08-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: methyl 15-(tert-butyldimethyl)silyloxy-8(R)-methoxy-11(R)-p-nitrobenzoyloxy-9(S),12(R)-oxy-eicosa-13-ynoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 15-(tert-butyldimethyl)silyloxy-8(R)-methoxy-11(R)-p-nitrobenzoyloxy-9(S),12(R)-oxy-eicosa-13-ynoate(76166-08-0)
• EPA Substance Registry System: methyl 15-(tert-butyldimethyl)silyloxy-8(R)-methoxy-11(R)-p-nitrobenzoyloxy-9(S),12(R)-oxy-eicosa-13-ynoate(76166-08-0)

Safety Data

• Hazardous Substances Data: 76166-08-0(Hazardous Substances Data)

Upstream product

• 60134-93-2 3-(tert-butyldimethylsilyloxy)oct-1-yne 
• 76145-27-2 methyl 12-bromo-8(R)-methoxy-11(R)-p-nitrobenzoyloxy-9(S),12-oxy-dodecanoate 
• 75824-59-8 (R)-8-((3aR,5S,6aR)-2,2-Dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-yl)-8-methoxy-oct-5-ynoic acid methyl ester 
• 76145-25-0 methyl 11(R),12-dihydroxy-8(R)-methoxy-9(S),12-oxy-dodecanoate 
• 122-04-3 4-nitro-benzoyl chloride 
• 818-72-4 1-Octyn-3-ol 
• 76145-26-1 methyl 11(R),12-di-p-benzoyloxy-8(R)-methoxy-9(S),12-oxy-dodecanoate 
• 76145-24-9 methyl 11(R),12(R)-isopropylidenedioxy-8(R)-methoxy-9(S),12(R)-oxy-dodecanoate 
• 18162-48-6 tert-butyldimethylsilyl chloride 

Downstream Products

• 76145-29-4 methyl 15-hydroxy-8(R)-methoxy-11(R)-p-nitrobenzoyloxy-9(S),12(R)-oxy-eicosa-13-ynoate 

Relevant articles and documents

Oxidation products of arachidonic acid. IV. Model studies on the attachment of the C(13)-C(20) side-chain in the synthesis of tetrahydrofurans and pyrans 1, 2, and 3

The synthesis of methyl 15-hydroxy-8(R)-methoxy-11(R)-p-nitrobenzoyloxy-9(S),12(R)-oxy-eicosa-13-ynoate, an arachidonic acid metabolite derivative, is described.As well, methods for the attachment of the C(13)-C(20) prostaglandin side-chain to furanosides were studied and the results are described.The reduction of the C-15 keto group on a model compound was performed and was found to have the same behavior as in the prostaglandins.A partial structure proof of Pace-Asciak's compound, 9,12-oxy-8,11,15-trihydroxy-13-enoic acid is given.