7620-28-2 Usage
Description
D-2-Aminoadipic acid, an optically active form of 2-aminoadipic acid with D-configuration, is a solid compound that serves as a glutamine synthetase inhibitor. This property makes it a potential candidate for various applications in different industries, particularly in the pharmaceutical and biotechnology sectors.
Uses
Used in Pharmaceutical Industry:
D-2-Aminoadipic acid is used as a pharmaceutical agent for its glutamine synthetase inhibitory properties. It plays a crucial role in modulating the activity of glutamine synthetase, an enzyme involved in the biosynthesis of glutamine from glutamate and ammonia. By inhibiting this enzyme, D-2-Aminoadipic acid can potentially be utilized in the development of therapeutic strategies for various diseases, including cancer and neurological disorders.
Used in Biotechnology Industry:
In the biotechnology industry, D-2-Aminoadipic acid can be employed as a research tool for studying the role of glutamine synthetase in cellular processes and its potential as a target for drug development. Its inhibitory effect on glutamine synthetase can provide valuable insights into the regulation of nitrogen metabolism and the development of novel therapeutic approaches.
Used in Drug Development:
D-2-Aminoadipic acid is used as a lead compound in drug development for its ability to inhibit glutamine synthetase. This inhibition can be leveraged to design and synthesize new drugs that target this enzyme, potentially leading to the development of more effective treatments for various diseases.
Used in Nutritional Supplements:
D-2-Aminoadipic acid may also find application in the development of nutritional supplements, particularly those aimed at supporting nitrogen metabolism and overall health. Its role in regulating glutamine synthesis could potentially contribute to improved athletic performance, muscle recovery, and overall well-being.
Check Digit Verification of cas no
The CAS Registry Mumber 7620-28-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,6,2 and 0 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 7620-28:
(6*7)+(5*6)+(4*2)+(3*0)+(2*2)+(1*8)=92
92 % 10 = 2
So 7620-28-2 is a valid CAS Registry Number.
InChI:InChI=1/C6H11NO4/c7-4(6(10)11)2-1-3-5(8)9/h4H,1-3,7H2,(H,8,9)(H,10,11)/t4-/m1/s1
7620-28-2Relevant articles and documents
Preparation method of beta-homoglutamic acid
-
Paragraph 0022; 0033-0034, (2020/11/05)
The invention belongs to the field of preparation of organic compounds, and provides a preparation method of beta-homoglutamic acid. The method is characterized in that: 3-cyclohexenecarboxylic acid is used as a raw material, beta-homoglutamic acid is synthesized at a high yield through three the steps of reactions of Curtius rearrangement, olefin oxidation and protection group removal, and beta-homoglutamic acid with high yield and high optical purity can be obtained through configuration retention by using optically pure 3-cyclohexenecarboxylic acid. The method has the advantages of easily available raw materials, mild reaction conditions and low cost, and is suitable for large-scale preparation of beta-homoglutamic acid.
VITAMIN COMPRISING PYROLOQUINOLINE QUINONE AND USE THEREOF
-
Page/Page column 20, (2008/06/13)
It is an object of the present invention to clarify the biochemical role of pyrroloquinoline quinone (PQQ) in living bodies by identifying an enzyme that uses PQQ as a coenzyme in mammals and then by clarifying the oxidation-reduction reaction, with which PQQ is associated as a coenzyme in living bodies. The present invention provides a method of using pyrroloquinoline quinone as a coenzyme for 2-aminoadipate 6-semialdehyde dehydrogenase.
TOTAL SYNTHESIS OF ENANTIOMERICALLY PURE D-α-AMINOADIPIC ACID
Amoroso, Rosa,Cardillo, Giuliana,Romero, Marta Susana,Tomasini, Claudia
, p. 75 - 78 (2007/10/02)
The diastereoselective cyclization of amidal (S,R)-2a, promoted by Hg(OTFA)2, afforded the imidazolidin-4-one (1'S,2R,5R)-3a as a single diastereoisomer. The subsequent transformation of the carbon-mercury bond and the acid hydrolysis of the heterocycle gave enantiomerically pure D-α-aminoadipic acid.
