76280-88-1

Basic information

• Product Name: 2-methyl-6-keto-6-(4-methyl-3-cyclohexen-1-yl)-2-hexene
• Synonyms: 2-methyl-6-keto-6-(4-methyl-3-cyclohexen-1-yl)-2-hexene
• CAS NO: 76280-88-1
• Molecular Weight: 206.328
• Mol File: 76280-88-1.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 2-methyl-6-keto-6-(4-methyl-3-cyclohexen-1-yl)-2-hexene(CAS DataBase Reference)
• NIST Chemistry Reference: 2-methyl-6-keto-6-(4-methyl-3-cyclohexen-1-yl)-2-hexene(76280-88-1)
• EPA Substance Registry System: 2-methyl-6-keto-6-(4-methyl-3-cyclohexen-1-yl)-2-hexene(76280-88-1)

Safety Data

• Hazardous Substances Data: 76280-88-1(Hazardous Substances Data)

Upstream product

• 115-18-4 2-methyl-3-buten-2-ol 
• 6090-11-5 3-(4-methyl-cyclohex-3-enyl)-3-oxo-propionic acid ethyl ester 
• 82096-08-0 5-Methyl-1-(4-trimethylsilanylmethyl-cyclohex-3-enyl)-hex-4-en-1-one 
• 6090-08-0 (R)-2-methyl-2-(4-methylcyclohex-3-en-1-yl)-1,3-dioxolane 
• 78-79-5 isoprene 
• 24903-94-4 7-methyl-1,6-octadiene-3-one 
• 4342-60-3 4-methylcyclohex-3-enecarboxylic acid 
• 6090-09-1 (+-)-4-acetyl-1-methylcyclohexene 
• 870-63-3 prenyl bromide 
• 64504-53-6 2-methylpent-2-en-5-yl lithium 
• 16695-95-7 (4'-methylcyclohex-3'-ene-1-'-yl)carbonyl chloride 
• 79673-97-5 1-(1-Oxo-2-methylsulfinylethyl)-4-methyl-3-cyclohexen 

Downstream Products

• 4891-79-6 β-bisabolene 
• 515-69-5 bisabolol 

Relevant articles and documents

Regioselective α-alkylation of silyl enolates using a mild catalyst- ZnCl2 doped on acidic alumina

ZnCl2 doped acidic alumina used as a solid support acts as a better Lewis acid in the S(N)1 reaction of trimethyl silyl enol ethers with 30, allylic and benzylic halides to yield exclusively the substituted product in excellent yields. This method has been employed for the synthesis of monocyclic sesquitepene hydrocarbon, (+)-β-bisabolene and a monoterpene, 2,6-dimethyl-7-octen-4-one.

ORGANOMANGANESE (II) REAGENTS XIV: A SHORT AND EFFICIENT SYNTHESIS OF DIASTEREOISOMERIC (+/-)-α-BISABOLOLS AND (+/-)-CHLORPHENOXAMINE

Diastereomeric (+/-)-α-bisabolols (7), a sesquiterpenoid alcohol, and (+/-)-chlorphenoxamine (12), an antihistamine, have been prepared in excellent yields.Both these short and convenient syntheses involve as a key step the one-pot elaboration of a dissymetrical tertiary alcohol via an organomanganese reagent (5 to 7 and 9 to 10 respectively).

HIGHLY REGIOSELECTIVE DIELS-ALDER REACTIONS OF 2-TRIMETHYLSILYLMETHYL-1,3-BUTADIENE CATALYZED BY A LEWIS ACID AND APPLICATIONS TO SYNTHESES OF TERPENES

2-Trimethylsilylmethyl-1,3-butadiene undergoes highly regioselective Diels-Alder reactions with dienophiles such as acrolein and methyl vinyl ketone catalyzed by aluminium chloride in which the "para" isomers are obtained almost exclusively.The adducts are converted readily to a variety of naturally occurring mono and sesquiterpenes.