76343-89-0

Basic information

• Product Name: Latrunculin A Methyl Ketal
• Synonyms: Latrunculin A Methyl Ketal
• CAS NO: 76343-89-0
• Molecular Weight: 435.585
• Mol File: 76343-89-0.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Latrunculin A Methyl Ketal(CAS DataBase Reference)
• NIST Chemistry Reference: Latrunculin A Methyl Ketal(76343-89-0)
• EPA Substance Registry System: Latrunculin A Methyl Ketal(76343-89-0)

Safety Data

• Hazardous Substances Data: 76343-89-0(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 76343-93-6 latrunculin A 
• 76343-93-6 Latrunculin A 
• 76343-93-6 Latrunculin A 
• 76343-93-6 Latrunculin-A 

Downstream Products

• 1220351-11-0 17-O-methyl-N-benzyllatrunculin A 
• 1220351-12-1 17-O-methyl-N-benzoyllatrunculin A 
• 1220351-13-2 17-O-methyl-N-(6'-methoxyphenylacetyl)latrunculin A 
• 76343-93-6 latrunculin A 

Relevant articles and documents

Latrunculin-Based Macrolides and Their Uses

Latrunculin derivatives are disclosed, as are anti-invasive and cytotoxic uses for latrunculins and latrunculin derivatives, and semisyntheses of latrunculin derivatives. The latrunculins and latrunculin derivatives are useful, for example, in treating cancers.

On the Chemistry of Latrunculins A and B

The chemical behavior of latrunculins A (1) and (B) (Lat A and B) under a variety of reaction conditions is described.The combination of the macrolide, the THP-lactol, and the 2-thiazolidinone rings was found to result on interesting unpredicted chemical transformations.The structures of two new Lats, 6,7-epoxy-Lat A (3) and Lat M (4) isolated from Latrunculia magnifica, are discussed.

Latrunculin, a new 2-thiazolidinone macrolide from the marine sponge latrunculia magnifica

Three new toxins were isolated from the Red Sea sponge Latrunculia magnifica A full structure determination of these toxins, by spectroscopic methods, was aided by an X-ray diffraction analysis of a crystalline derivative (1b) of latrunculin-A. The Latrunculins exhibit a new class of 14 and 16 membered macrolides to which the rare 2-thiazolidinone moiety is attached. A biogenesis of these biologically active compounds is put forward.