76360-43-5

Basic information

• Product Name: Methyl 2-bromothiophene-3-carboxylate
• Synonyms: 2-BroMo-thiophene-3-carboxylic acid Methyl ester;Methyl 2-broMothiophene-3-carboxylate
• CAS NO: 76360-43-5
• Molecular Formula: C₆H₅BrO₂S
• Molecular Weight: 221
• Mol File: 76360-43-5.mol
• Article Data: 31

Chemical Properties

• Boiling Point: 114-115 °C(Press: 4 Torr)
• Appearance: /
• Density: 1.662±0.06 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• CAS DataBase Reference: Methyl 2-bromothiophene-3-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl 2-bromothiophene-3-carboxylate(76360-43-5)
• EPA Substance Registry System: Methyl 2-bromothiophene-3-carboxylate(76360-43-5)

Safety Data

• Hazardous Substances Data: 76360-43-5(Hazardous Substances Data)

Usage

General Description

Methyl 2-bromothiophene-3-carboxylate is a chemical compound with the molecular formula C8H7BrO2S. It is a derivative of thiophene, a five-membered heterocyclic aromatic ring containing a sulfur atom. Methyl 2-bromothiophene-3-carboxylate is a brominated ester, meaning it contains a bromine atom and a carboxylate functional group. It is primarily used as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and organic compounds. Methyl 2-bromothiophene-3-carboxylate is a versatile building block in organic chemistry and is commonly used in the production of a variety of fine chemicals and pharmaceuticals with therapeutic applications.

Upstream product

• 186581-53-3 diazomethane 
• 24287-95-4 2-bromothiophene-3-carboxylic acid 
• 89280-91-1 2,5-dibromothiophene-3-carboxylic acid methyl ester 
• 67-56-1 methanol 
• 197370-13-1 2-bromo-3-thiophene carboxylic acid chloride 
• 498-62-4 3-thiophene carboxaldehyde 
• 74-88-4 methyl iodide 
• 18107-18-1 diazomethyl-trimethyl-silane 
• 88-13-1 3-Thiophene carboxylic acid 

Downstream Products

• 1254709-94-8 methyl 2-(4-fluoro-3-methylphenyl)thiophene-3-carboxylate 
• 1254709-93-7 methyl 2-(3-methyl-4-nitrophenyl)thiophene-3-carboxylate 
• 1395044-62-8 C₂₀H₁₈O₆S₂ 
• 1384579-71-8 7-iodo-6-phenyl-4H-thieno[3,2-c]pyran-4-one 
• 1295502-12-3 5H-dithieno[3,2-b:2',3'-d]pyran-5-one 
• 4751-59-1 5,6,7,8-tetrahydro-4H-thieno[3,2-c]azepine-4-one 
• 1395044-63-9 C₂₀H₁₆Br₂O₆S₂ 
• 1395044-64-0 C₅₂H₇₀O₆S₄ 
• 1009827-27-3 4-oxo-4,5-dihydrothieno[3,2-c]quinoline-7-carbonitrile 
• 859492-59-4 (+/-)-2-(2-methyl-6-nitro-phenyl)-thiophene-3-carboxylic acid 

Relevant articles and documents

PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS

Compounds of the formula (I) wherein the substituents are as defined in claim 1. Furthermore, the present invention relates to agrochemical compositions which comprise compounds of formula (I), to preparation of these compositions, and to the use of the compounds or compositions in agriculture or horticulture for combating, preventing or controlling animal pests, including arthropods and in particular insects, moluscs, nematodes or representatives of the order Acarina.

An attempt to synthesize a terthienyl-based analog of indacenedithiophene (IDT): unexpected synthesis of a naphtho[2,3-b]thiophene derivative

We report herein our attempt to synthesize an analog of indacenedithiophene (IDT) based on a tetraphenylhexyl substituted, covalently bridgedsyn-terthienyl unit. Instead of the expected compound the adopted synthetic route led to the formation of an unexpected, new naphtho[2,3-b]thiophene derivative. The structure of this compound was fully characterized by NMR and HRMS as well as single crystal X-ray diffraction and its electronic properties have been analyzed by UV-vis absorption spectroscopy and cyclic voltammetry. A possible mechanism for the formation of this compound is also proposed on the basis of detailed theoretical investigations.

ERK INHIBITORS

The present invention provides thieno[2,3-c]pyrrol-4-one compounds that inhibit activity of extracellular-signal-regulated kinase (ERK) and may be useful in the treatment of cancer.