76958-58-2

Basic information

• Product Name: [1,2,4]Triazol-1-yl-phosphonic acid (2R,3S,5R)-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-yl ester 2-chloro-phenyl ester
• Synonyms: [1,2,4]Triazol-1-yl-phosphonic acid (2R,3S,5R)-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-yl ester 2-chloro-phenyl ester
• CAS NO: 76958-58-2
• Molecular Weight: 786.178
• Mol File: 76958-58-2.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: [1,2,4]Triazol-1-yl-phosphonic acid (2R,3S,5R)-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-yl ester 2-chloro-phenyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: [1,2,4]Triazol-1-yl-phosphonic acid (2R,3S,5R)-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-yl ester 2-chloro-phenyl ester(76958-58-2)
• EPA Substance Registry System: [1,2,4]Triazol-1-yl-phosphonic acid (2R,3S,5R)-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-yl ester 2-chloro-phenyl ester(76958-58-2)

Safety Data

• Hazardous Substances Data: 76958-58-2(Hazardous Substances Data)

Upstream product

• 15074-54-1 2-chlorophenyl dichlorophosphate 
• 50-89-5 thymidine 
• 40615-36-9 4,4'-dimethoxytrityl chloride 
• 72351-28-1 2-chlorophenyl phosphordi(1H-1-[1,2,4]triazolide) 
• 40615-39-2 5'-O-(4-4'-dimethoxytrityl)thymidine 

Downstream Products

• 78129-28-9 C₆₂H₅₈Cl₂N₆O₁₇P₂ 
• 78150-12-6 C₆₂H₅₈Cl₂N₆O₁₇P₂ 
• 95833-26-4 C₅₉H₅₅Cl₂N₅O₁₇P₂*C₆H₁₅N 
• 78111-49-6 C₆₃H₅₈Cl₂N₈O₁₆P₂ 
• 78129-27-8 C₆₀H₆₀Cl₂N₈O₁₇P₂ 
• 95061-24-8 C₅₉H₅₅Cl₂N₅O₁₇P₂*C₆H₁₅N 
• 94940-31-5 C₆₀H₅₅Cl₂N₇O₁₆P₂*C₆H₁₅N 
• 94940-30-4 C₅₇H₅₇Cl₂N₇O₁₇P₂*C₆H₁₅N 

Relevant articles and documents

The photochemistry of thymidylyl-(3′-5′)-5-methyl-2′- deoxycytidine in aqueous solution

The photochemistry of the dinudeoside monophosphate thymidylyl-(3′- 5′)-5-methyl-2′-deoxycytidine (Tpm5dC) has been studied in aqueous solution using both 254 nm and UV-B radiation. A variety of dinucleotide photoproducts containing 5-methyl-cy

ON THE PHOSPHORYLATION OF DEOXYRIBONUCLEOSIDES AND THE PROTECTION OF DEOXYGUANOSINE

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Simplified Liquid-Phase Preparation of Four Decadeoxyribonucleotides and their Preliminary Spectroscopic Characterization

Four self-complementary decadeoxyribonucleotides, dApTpApTpApTpApTpApT,dApTpApTpCpGpApTpApT, dApTpApTpGpCpApTpApT and dApApApApApTpTpTpTpT, were chemically synthesized by the phosphotriester procedure.Efforts were concentrated on keeping the procedure as simple as possible, concomitant with obtaining high-purity products at each step of the process.The decamers were elaborated from the 3'-end, starting with a 3'-O-benzoylated monomer according to the scheme: monomer + monomer -> dimer + dimer -> tetramer + dimer -> hexamer + tetramer -> decamer.Putity of intermediates and of the fully blocked decamers were monitored by chromatography and by 300-MHz 1H-NMR. spectroscopy.The deblocked decadeoxyribonucleotides were characterized by their UV., CD., and 1H-NMR. spectra.