77620-46-3

Basic information

• Product Name: (3beta,4alpha)-15-(acetyloxy)-3-hydroxy-12,13-epoxytrichothec-9-en-4-yl chloroacetate
• CAS NO: 77620-46-3
• Molecular Formula: C₁₉H₂₅ClO₇
• Molecular Weight: 400.8506
• Mol File: 77620-46-3.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 506.2°C at 760 mmHg
• Flash Point: 260°C
• Density: 1.38g/cm³
• Vapor Pressure: 2.28E-12mmHg at 25°C
• Refractive Index: 1.569
• CAS DataBase Reference: (3beta,4alpha)-15-(acetyloxy)-3-hydroxy-12,13-epoxytrichothec-9-en-4-yl chloroacetate(CAS DataBase Reference)
• NIST Chemistry Reference: (3beta,4alpha)-15-(acetyloxy)-3-hydroxy-12,13-epoxytrichothec-9-en-4-yl chloroacetate(77620-46-3)
• EPA Substance Registry System: (3beta,4alpha)-15-(acetyloxy)-3-hydroxy-12,13-epoxytrichothec-9-en-4-yl chloroacetate(77620-46-3)

Safety Data

• Hazardous Substances Data: 77620-46-3(Hazardous Substances Data)

Usage

Description

(3beta,4alpha)-15-(acetyloxy)-3-hydroxy-12,13-epoxytrichothec-9-en-4-yl chloroacetate is a type of trichothecene mycotoxin, a toxic compound produced by certain types of fungi. This chemical compound features a trichothecene skeleton with an epoxide ring and a chlorine atom, as well as an acetoxy and hydroxy group. Trichothecene mycotoxins are recognized for their potent toxicity, leading to a range of adverse health effects in humans and animals, such as inhibition of protein synthesis, immune system suppression, and gastrointestinal issues.

Uses

Used in Agricultural and Food Safety Settings:
(3beta,4alpha)-15-(acetyloxy)-3-hydroxy-12,13-epoxytrichothec-9-en-4-yl chloroacetate is used as a monitoring agent for assessing the presence of trichothecene mycotoxins in agricultural products and food items. Its detection is crucial for ensuring food safety and preventing the consumption of contaminated products that can lead to severe health issues.
Used in Research and Development:
In the scientific community, (3beta,4alpha)-15-(acetyloxy)-3-hydroxy-12,13-epoxytrichothec-9-en-4-yl chloroacetate serves as a valuable research tool for studying the mechanisms of trichothecene toxicity and developing strategies to mitigate their harmful effects. This includes the development of methods for decontamination, the creation of resistant crop varieties, and the discovery of potential antidotes or treatments for trichothecene poisoning.
Used in Environmental Monitoring:
(3beta,4alpha)-15-(acetyloxy)-3-hydroxy-12,13-epoxytrichothec-9-en-4-yl chloroacetate is also utilized in environmental monitoring programs to detect the presence of toxic fungi in the ecosystem. This helps in understanding the spread of these fungi and implementing measures to control their growth and prevent their impact on human and animal health.

Upstream product

• 77620-40-7 4β,15-diacetoxy-3α-O-(2-tetrahydropyranyl)scirpene 
• 77620-42-9 15-acetoxy-3α-O-(2-tetrahydropyranyl)scirpen-4β-ol 
• 2270-40-8 anguidine 
• 77620-60-1 15-acetoxy-4β-(chloroacetoxy)-3α-O-(2-tetrahydropyranyl)scirpene 

Downstream Products

• 79320-84-6 15-acetoxy-4β-(chloroacetoxy)scirpen-3-one 
• 77620-56-5 15-acetoxy-4β-(chloroacetoxy)scirpene-3α,8β-diol 
• 77620-57-6 15-acetoxy-4β-(chloroacetoxy)scirpene-3,8-dione 
• 79320-84-6 15-Acetoxy-4β-chloroacetoxy-12,13-epoxytrichothec-9-en-3-one 
• 77620-56-5 15-acetoxy-4β-chloroacetoxy-3α,8β-dihydroxy-12,13-epoxytrichothec-9-ene 

Relevant articles and documents

Structural modifications of anguidin and antitumor activities of its analogues

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