777-70-8

Basic information

• Product Name: (3-FLUOROPHENOXY) ACETIC ACID ETHYL ESTER
• Synonyms: (3-FLUOROPHENOXY) ACETIC ACID ETHYL ESTER
• CAS NO: 777-70-8
• Molecular Formula: C₁₀H₁₁FO₃
• Molecular Weight: 198.19
• Mol File: 777-70-8.mol
• Article Data: 13

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (3-FLUOROPHENOXY) ACETIC ACID ETHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: (3-FLUOROPHENOXY) ACETIC ACID ETHYL ESTER(777-70-8)
• EPA Substance Registry System: (3-FLUOROPHENOXY) ACETIC ACID ETHYL ESTER(777-70-8)

Safety Data

• Hazardous Substances Data: 777-70-8(Hazardous Substances Data)

Usage

General Description

(3-Fluorophenoxy) acetic acid ethyl ester is a chemical compound with the molecular formula C10H11FO3. It is an ethyl ester of (3-fluorophenoxy) acetic acid, a derivative of acetic acid. (3-FLUOROPHENOXY) ACETIC ACID ETHYL ESTER is a liquid with a strong, sweet odor and is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. Its structure includes a fluorine atom attached to a phenyl ring and an ethyl group connected to the carboxylic acid moiety. (3-Fluorophenoxy) acetic acid ethyl ester has various industrial applications but should be handled with caution due to its potential health and environmental hazards.

Upstream product

• 372-20-3 3-fluorophenol 
• 105-39-5 chloroacetic acid ethyl ester 
• 105-36-2 ethyl bromoacetate 

Downstream Products

• 863250-70-8 2-(3-fluoro-phenoxy)-3-oxo-succinic acid diethyl ester 
• 1263183-87-4 C₁₃H₁₀FN₃O₂S 
• 1052694-73-1 2-{[(3-fluorophenyl)oxy]acetyl}hydrazinecarbonylthioamide 
• 379255-56-8 2-(3-fluorophenoxy)acetic acid hydrazide 
• 95299-69-7 2-(3-fluorophenoxy)acetyl chloride 
• 404-98-8 3-fluorophenoxyacetic acid 

Relevant articles and documents

Synthesis and larvicidal activity of 1,3,4-oxadiazole derivatives containing a 3-chloropyridin-2-yl-1H-pyrazole scaffold

Abstract: A new series of 1,3,4-oxadiazole derivatives with a 3-chloropyridin-2-yl-1H-pyrazole moiety was designed, synthesized, and characterized. The results of bioassay against Helicoverpa armigera and Plutella xylostella indicated that some of the synthesized compounds showed remarkable larvicidal activity. In particular, the LC50 values of the most active compounds against P. xylostella were 46.5, 23.9, and 13.9?mg/dm3, and against Helicoverpa armigera were 88.3 and 69.5?mg/dm3, the latter being slightly better than commercial chlorpyrifos (LC50 103.77?mg/dm3). Preliminary SAR was also discussed. Graphical abstract: [Figure not available: see fulltext.].

Synthesis and biological activity of 1-(Substituted phenoxyacetoxy)- 1-(pyridin-2-yl or thien-2-yl)methylphosphonates

A series of novel O,O-dimethyl 1-(substituted phenoxyacetoxy)-1-(pyridin-2-yl or thien-2-yl)methylphosphonates 6a-n and 7a-d were synthesized. Their structures were confirmed by IR, 1H NMR, mass spectroscopy, and elemental analyses. The results of preliminary bioassays show that some of the title compounds exhibit moderate to good herbicidal and fungicidal activities. For example, the title compounds 6a, 6c, 6l, 6m, and 7d possess 90-100% inhibition against most of the tested plants at the dosage of 1500 g ai/ha, whereas the title compounds 6b, 6g-h and 6n possess 92-100% inhibition against Fusarium oxysporum, Phyricularia grisea, Botrytis cinereapers, Gibberella zeae, Sclerotinia sclerotiorum, and Cercospora beticola at the concentration of 50mg/L.

QUINOLINONE DERIVATIVES

The present invention relates to compounds of the formula (I), salts thereof, to pharmaceutical compositions containing them and their use in medicine. In particular, the invention relates to compounds as activators of AMPK.